Findings

What do systematic reviews say?

5 questions · 5 findings · 2 reviews · Oral medicine and oral cancer

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No studies found 1 · 20%GRADE not reported 4 · 80%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Antifungal drugs absorbed from GI tract (fluconazole, ketoconazole, itraconazole) vs Antifungal drugs not absorbed from GI tract

Systemic fungal infection · Patients with cancer receiving chemotherapy and/or radiotherapy

Antifungal drugs absorbed from GI tract showed no clear difference in systemic fungal infection compared with antifungal drugs not absorbed from GI tract; GRADE not reported.

1 finding from 1 review

Interventions for preventing oral candidiasis for patients with cancer receiving treatment 2007 · Cochrane All outcomes
RR 0.59 [0.33, 1.06]
8 studies · 2103 participants
GRADE not reported

Any antifungal intervention for the treatment of oral candidiasis vs Placebo, no treatment, or another active antifungal intervention

Incidence of systemic infection · Patients with cancer receiving chemotherapy and/or radiotherapy with overt oral candidiasis

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for treating oral candidiasis for patients with cancer receiving treatment 2010 · Cochrane All outcomes
None of the studies reported: relief of pain, relief of dysphagia, incidence of systemic infection, amount of analgesia, days stay in hospital, cost of oral care, patient quality of life.
0 studies
No studies found

Antifungal drugs not absorbed from GI tract vs placebo or no treatment

Systemic fungal infection · Patients with cancer receiving chemotherapy and/or radiotherapy

Antifungal drugs not absorbed from GI tract showed no clear difference in systemic fungal infection compared with placebo or no treatment; GRADE not reported.

1 finding from 1 review

Interventions for preventing oral candidiasis for patients with cancer receiving treatment 2007 · Cochrane All outcomes
RR 0.1 [0.01, 1.75]
2 studies · 71 participants
GRADE not reported

Antifungal drugs partially absorbed from GI tract (miconazole, clotrimazole) vs placebo or no treatment

Systemic fungal infection · Patients with cancer receiving chemotherapy and/or radiotherapy

Antifungal drugs partially absorbed from GI tract (miconazole,… showed no clear difference in systemic fungal infection compared with placebo or no treatment; GRADE not reported.

1 finding from 1 review

Interventions for preventing oral candidiasis for patients with cancer receiving treatment 2007 · Cochrane All outcomes
RR 2.27 [0.23, 22.56]
1 study · 32 participants
GRADE not reported

Antifungal drugs absorbed from GI tract (fluconazole, ketoconazole, itraconazole) vs placebo or no treatment

Systemic fungal infection · Patients with cancer receiving chemotherapy and/or radiotherapy

Antifungal drugs absorbed from GI tract (fluconazole, ketoconazole,… showed no clear difference in systemic fungal infection compared with placebo or no treatment; GRADE not reported.

1 finding from 1 review

Interventions for preventing oral candidiasis for patients with cancer receiving treatment 2007 · Cochrane All outcomes
RR 0.65 [0.37, 1.14]
6 studies · 1041 participants
GRADE not reported