Summary of findings for cholinesterase inhibitors vs placebo
Quality of life immediately after the intervention · people with Parkinson's disease
1 finding from 1 review
- no estimate extracted1 study · 121 participantsVery low
Findings
What do systematic reviews say?
6 questions · 6 findings · 1 reviews
No studies found 1 · 16.7%GRADE not reported 0 · 0%Very low 3 · 50%Low 2 · 33.3%Moderate 0 · 0%High 0 · 0%
Summary of findings for cholinesterase inhibitors vs placebo
Rate of adverse events excluding falls (per person year) · people with Parkinson's disease
Summary of findings for cholinesterase inhibitors may leads to higher rate of adverse events excluding falls (per person year) compared with placebo (low certainty).
1 finding from 1 review
- Rate ratio 1.6 [1.28, 2.01]2 studies · 175 participantsLow
Summary of findings for cholinesterase inhibitors vs placebo
Economic outcomes · people with Parkinson's disease
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Summary of findings for cholinesterase inhibitors vs placebo
Falls · people with Parkinson's disease
Summary of findings for cholinesterase inhibitors may leads to lower rate of falls (falls per person‐year) compared with placebo (low certainty).
1 finding from 1 review
- Rate ratio 0.5 [0.44, 0.58]3 studies · 229 participantsLow
Summary of findings for cholinesterase inhibitors vs placebo
Number of people who experienced one or more falls · people with Parkinson's disease
1 finding from 1 review
- no estimate extracted3 studies · 230 participantsVery low
Summary of findings for cholinesterase inhibitors vs placebo
Number of people sustaining one or more fall‐related fractures · people with Parkinson's disease
1 finding from 1 review
- no estimate extracted1 study · 23 participantsVery low