Findings

What do systematic reviews say?

7 questions · 7 findings · 1 reviews

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No studies found 4 · 57.1%GRADE not reported 0 · 0%Very low 2 · 28.6%Low 1 · 14.3%Moderate 0 · 0%High 0 · 0%

Summary of findings: nitric oxide vs placebo

Pulmonary exacerbations · children (12 or over) and young adults with cystic fibrosis

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotic adjuvant therapy for pulmonary infection in cystic fibrosis 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings: nitric oxide vs placebo

FEV1 (% predicted): mean change from baseline · children (12 or over) and young adults with cystic fibrosis

Summary of findings: nitric oxide showed no clear difference in respiratory function mean change in FEV1 % predicted from baseline compared with placebo (low certainty).

1 finding from 1 review

Antibiotic adjuvant therapy for pulmonary infection in cystic fibrosis 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 12 participants
Low

Summary of findings: nitric oxide vs placebo

Adverse events · children (12 or over) and young adults with cystic fibrosis

It is very uncertain whether summary of findings: nitric oxide changes adverse events compared with placebo (very low certainty).

1 finding from 1 review

Antibiotic adjuvant therapy for pulmonary infection in cystic fibrosis 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 30 participants
Very low

Summary of findings: nitric oxide vs placebo

Need for antibiotics · children (12 or over) and young adults with cystic fibrosis

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotic adjuvant therapy for pulmonary infection in cystic fibrosis 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings: nitric oxide vs placebo

QoL · children (12 or over) and young adults with cystic fibrosis

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotic adjuvant therapy for pulmonary infection in cystic fibrosis 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings: nitric oxide vs placebo

Sputum microbiology · children (12 or over) and young adults with cystic fibrosis

1 finding from 1 review

Antibiotic adjuvant therapy for pulmonary infection in cystic fibrosis 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 30 participants
Very low

Summary of findings: nitric oxide vs placebo

Inflammatory markers · children (12 or over) and young adults with cystic fibrosis

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotic adjuvant therapy for pulmonary infection in cystic fibrosis 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found