Findings

What do systematic reviews say?

4 questions · 4 findings · 1 reviews

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No studies found 2 · 50%GRADE not reported 0 · 0%Very low 1 · 25%Low 1 · 25%Moderate 0 · 0%High 0 · 0%

Summary of findings: Proteolytic enzymes vs placebo or control

Mean GI symptom scores · People undergoing RT for pelvic cancer

The review found no eligible studies for this question.

1 finding from 1 review

Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary pelvic… 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings: Proteolytic enzymes vs placebo or control

Acute and late GI toxicity (grade 2+) · People undergoing RT for pelvic cancer

Summary of findings: Proteolytic enzymes may leads to lower acute and late GI toxicity (grade 2+) compared with control (placebo or no intervention) (low certainty).

1 finding from 1 review

Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary pelvic… 2018 · Cochrane Headline outcomes only
RR 0.45 [0.24, 0.88]
1 study · 120 participants
Low

Summary of findings: Proteolytic enzymes vs placebo or control

Diarrhoea (grade 2+) · People undergoing RT for pelvic cancer

It is very uncertain whether summary of findings: Proteolytic enzymes changes diarrhoea (grade 2+) compared with control (placebo or no intervention) (very low certainty).

1 finding from 1 review

Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary pelvic… 2018 · Cochrane Headline outcomes only
RR 1.6 [0.89, 2.89]
1 study · 56 participants
Very low

Summary of findings: Proteolytic enzymes vs placebo or control

QoL · People undergoing RT for pelvic cancer

The review found no eligible studies for this question.

1 finding from 1 review

Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary pelvic… 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found