Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

19 questions · 19 findings · 2 reviews

No studies found 4 · 21.1%GRADE not reported 0 · 0%Very low 1 · 5.3%Low 4 · 21.1%Moderate 10 · 52.6%High 0 · 0%

Insulin glargine vs NPH insulin

Severe nocturnal hypoglycaemia (n/N) Definition: severe hypoglycaemia occurring 00:01‐05:59 (Davies 2014) or 23:00‐07:00 (BEGIN Young)

Summary of findings: insulin glargine showed no clear difference in severe nocturnal hypoglycaemia (n/N) Definition: severe… compared with NPH insulin (moderate certainty).

1 finding from 1 review

Summary of findings: insulin detemir vs NPH insulin

Severe nocturnal hypoglycaemia (n/N) Definition: severe hypoglycaemia occurring 00:01‐05:59 (Davies 2014) or 23:00‐07:00 (BEGIN Young)

Summary of findings: insulin detemir showed no clear difference in severe nocturnal hypoglycaemia (n/N) Definition: severe… compared with NPH insulin (moderate certainty).

1 finding from 1 review