Findings

What do systematic reviews say?

8 questions · 8 findings · 1 reviews · Kidney and Transplant

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No studies found 4 · 50%GRADE not reported 0 · 0%Very low 1 · 12.5%Low 2 · 25%Moderate 1 · 12.5%High 0 · 0%

Summary of findings: Iron vs placebo or usual care

Death (all causes) · people with CKD

Summary of findings: Iron showed no clear difference in death (all causes) compared with placebo/usual care (low certainty).

1 finding from 1 review

Phosphate binders for preventing and treating chronic kidney disease‐mineral and bone disorder (CKD‐MBD) 2018 · Cochrane Headline outcomes only
RR 0.52 [0.06, 4.65]
2 studies · 239 participants
Low

Summary of findings: Iron vs placebo or usual care

Cardiovascular mortality · people with CKD

The review found no eligible studies for this question.

1 finding from 1 review

Phosphate binders for preventing and treating chronic kidney disease‐mineral and bone disorder (CKD‐MBD) 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings: Iron vs placebo or usual care

Hypercalcaemia · people with CKD

The review found no eligible studies for this question.

1 finding from 1 review

Phosphate binders for preventing and treating chronic kidney disease‐mineral and bone disorder (CKD‐MBD) 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings: Iron vs placebo or usual care

Nausea · people with CKD

It is very uncertain whether summary of findings: Iron changes nausea compared with placebo/usual care (very low certainty).

1 finding from 1 review

Phosphate binders for preventing and treating chronic kidney disease‐mineral and bone disorder (CKD‐MBD) 2018 · Cochrane Headline outcomes only
RR 0.99 [0.3, 3.27]
1 study · 149 participants
Very low

Summary of findings: Iron vs placebo or usual care

Vomiting · people with CKD

The review found no eligible studies for this question.

1 finding from 1 review

Phosphate binders for preventing and treating chronic kidney disease‐mineral and bone disorder (CKD‐MBD) 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings: Iron vs placebo or usual care

Constipation · people with CKD

Summary of findings: Iron probably leads to higher constipation compared with placebo/usual care (moderate certainty).

1 finding from 1 review

Phosphate binders for preventing and treating chronic kidney disease‐mineral and bone disorder (CKD‐MBD) 2018 · Cochrane Headline outcomes only
RR 2.66 [1.15, 6.12]
3 studies · 422 participants
Moderate

Summary of findings: Iron vs placebo or usual care

Serum phosphate level · people with CKD

1 finding from 1 review

Phosphate binders for preventing and treating chronic kidney disease‐mineral and bone disorder (CKD‐MBD) 2018 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 422 participants
Low

Summary of findings: Iron vs placebo or usual care

Coronary artery calcification score · people with CKD

The review found no eligible studies for this question.

1 finding from 1 review

Phosphate binders for preventing and treating chronic kidney disease‐mineral and bone disorder (CKD‐MBD) 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found