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What do systematic reviews say?

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Evidence found and GRADE certainty

7 questions · 7 findings · 1 reviews

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No studies found 4 · 57.1%GRADE not reported 0 · 0%Very low 3 · 42.9%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Sulthiame add‐on vs placebo

50% or greater reduction in seizure frequency · patients between 3 to 15 months of age with West syndrome

The review found no eligible studies for this question.

1 finding from 1 review

Sulthiame add‐on vs placebo

Complete cessation of seizures 9 days · patients between 3 to 15 months of age with West syndrome

It is very uncertain whether sulthiame add‐on changes complete cessation of seizures during compared with placebo (very low certainty).

1 finding from 1 review

Sulthiame add‐on vs placebo

Number experiencing adverse effects · patients between 3 to 15 months of age with West syndrome

It is very uncertain whether sulthiame add‐on changes adverse effects: total number of participants experiencing one or… compared with placebo (very low certainty).

1 finding from 1 review

Sulthiame add‐on vs placebo

Somnolence · patients between 3 to 15 months of age with West syndrome

It is very uncertain whether sulthiame add‐on changes adverse effects: somnolence compared with placebo (very low certainty).

1 finding from 1 review