Ototoxicity according to Brock criteria with intravenous platinum (combined asymptomatic and symptomatic disease) · children with cancer treated with platinum‐based therapy
Sodium thiosulfate probably leads to lower ototoxicity according to Brock criteria with intravenous platinum… compared with no otoprotective intervention (moderate certainty).
1 finding from 1 review
Survival · children with cancer treated with platinum‐based therapy
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Overall survival with intravenous platinum (i.e. mortality/number of participants deceased) · children with cancer treated with platinum‐based therapy
Sodium thiosulfate showed no clear difference in overall survival with intravenous platinum (i.e. mortality/number of… compared with no otoprotective intervention (low certainty).
1 finding from 1 review
Event‐free survival · children with cancer treated with platinum‐based therapy
Sodium thiosulfate showed no clear difference in event‐free survival with intravenous platinum (i.e. number of… compared with no otoprotective intervention (low certainty).
1 finding from 1 review
Tumour response · children with cancer treated with platinum‐based therapy
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Tumour response with intravenous platinum (complete and partial remission) · children with cancer treated with platinum‐based therapy
Sodium thiosulfate showed no clear difference in tumour response with intravenous platinum (complete and partial… compared with no otoprotective intervention (low certainty).
1 finding from 1 review
Adverse effects other than ototoxicity (≥ grade 3 according to NCICTCAEv3 criteria) with intravenous platinum · children with cancer treated with platinum‐based therapy
1 finding from 1 review
Quality of life · children with cancer treated with platinum‐based therapy
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Quality of life ‐ not reported · children with cancer treated with platinum‐based therapy
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found