What do systematic reviews say?

Methadone vs oral slow‐release morphine

• Maintenance agonist treatments for opiate‐dependent pregnant women 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 48 participants
  Low

Methadone vs oral slow‐release morphine

The review found no eligible studies for this question.

• Maintenance agonist treatments for opiate‐dependent pregnant women 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Methadone vs oral slow‐release morphine

• Maintenance agonist treatments for opiate‐dependent pregnant women 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 48 participants
  Low

Methadone vs oral slow‐release morphine

• Maintenance agonist treatments for opiate‐dependent pregnant women 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 48 participants
  Low

Methadone vs oral slow‐release morphine

• Maintenance agonist treatments for opiate‐dependent pregnant women 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 48 participants
  Low

Methadone vs oral slow‐release morphine

Methadone showed no clear difference in use of substance compared with oral slow‐release morphine (low certainty).

• Maintenance agonist treatments for opiate‐dependent pregnant women 2020 · Cochrane Headline outcomes only
  RR 2.4 [1, 5.77]
  1 study · 48 participants
  Low

Rapid vs slow taper of buprenorphine dose

It is very uncertain whether rapid changes completion of withdrawal treatment − Outpatient compared with slow taper of buprenorphine dose (very low certainty).

• Buprenorphine for managing opioid withdrawal 2017 · Cochrane Headline outcomes only
  RR 0.86 [0.44, 1.7]
  4 studies · 647 participants
  Very low

Rapid vs slow taper of buprenorphine dose

Rapid showed no clear difference in number abstinent at completion of dose taper − Inpatient compared with slow taper of buprenorphine dose (low certainty).

• Buprenorphine for managing opioid withdrawal 2017 · Cochrane Headline outcomes only
  RR 1 [0.81, 1.23]
  1 study · 40 participants
  Low

Rapid vs slow taper of buprenorphine dose

It is very uncertain whether rapid changes number abstinent at completion of dose taper − Outpatient compared with slow taper of buprenorphine dose (very low certainty).

• Buprenorphine for managing opioid withdrawal 2017 · Cochrane Headline outcomes only
  RR 0.94 [0.39, 2.24]
  4 studies · 619 participants
  Very low

Rapid vs slow taper of buprenorphine dose

Rapid showed no clear difference in completion of withdrawal treatment − Inpatient compared with slow taper of buprenorphine dose (low certainty).

• Buprenorphine for managing opioid withdrawal 2017 · Cochrane Headline outcomes only
  RR 1 [0.84, 1.18]
  2 studies · 60 participants
  Low