Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

13 questions · 13 findings · 4 reviews · All outcomes

No studies found 1 · 7.7%GRADE not reported 6 · 46.2%Very low 6 · 46.2%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Single-stage alginate impression (simplified method) vs Two stage-two step zinc-oxide eugenol (ZoE) traditional method

Participant-reported quality of the denture (general satisfaction) · Completely edentulous people

It is very uncertain whether single-stage alginate impression (simplified method) changes participant-reported quality of the denture (general satisfaction) compared with two stage-two step zinc-oxide eugenol (ZoE) traditional method (very low certainty).

1 finding from 1 review

Single-stage alginate impression (simplified method) vs Two stage-two step elastomer (silicone, polysulfide, or polyether) conventional method

Operator-assessed quality of the denture · Completely edentulous people
1 finding from 1 review

Single-stage alginate impression (simplified method) vs Two stage-two step elastomer (silicone, polysulfide, or polyether) conventional method

Participant-reported quality of the denture (general satisfaction) · Completely edentulous people

It is very uncertain whether single-stage alginate impression (simplified method) changes participant-reported quality of the denture (general satisfaction,… compared with two stage-two step elastomer (silicone, polysulfide, or polyether)… (very low certainty).

1 finding from 1 review

Single-stage alginate impression (simplified method) vs Two stage-two step zinc-oxide eugenol (ZoE) traditional method

Oral health-related quality of life · Completely edentulous people

It is very uncertain whether single-stage alginate impression (simplified method) changes participant-reported oral health-related quality of life (OHIP-EDENT) compared with two stage-two step zinc-oxide eugenol (ZoE) traditional method (very low certainty).

1 finding from 1 review

Single-stage alginate impression (simplified method) vs Two stage-two step elastomer (silicone, polysulfide, or polyether) conventional method

Mandibular denture satisfaction · Completely edentulous people

It is very uncertain whether single-stage alginate impression (simplified method) changes mandibular denture satisfaction compared with two stage-two step elastomer (silicone, polysulfide, or polyether)… (very low certainty).

1 finding from 1 review

Single-stage alginate impression (simplified method) vs Two stage-two step elastomer (silicone, polysulfide, or polyether) conventional method

Maxillary denture satisfaction · Completely edentulous people

It is very uncertain whether single-stage alginate impression (simplified method) changes maxillary denture satisfaction compared with two stage-two step elastomer (silicone, polysulfide, or polyether)… (very low certainty).

1 finding from 1 review

Single-stage alginate impression (simplified method) vs Two stage-two step elastomer (silicone, polysulfide, or polyether) conventional method

Oral health-related quality of life · Completely edentulous people

It is very uncertain whether single-stage alginate impression (simplified method) changes participant-reported oral health-related quality of life (OHIP-EDENT) compared with two stage-two step elastomer (silicone, polysulfide, or polyether)… (very low certainty).

1 finding from 1 review

Single-stage alginate impression (simplified method) vs Two stage-two step zinc-oxide eugenol (ZoE) traditional method

Operator-assessed quality of the denture (retention and stability) · Completely edentulous people
1 finding from 1 review

Simplified caries prediction models (>=2 predictors; microbiome-primary studies excluded), but some pooled models include microbe predictors (Yaxuan 2023: S. mutans; Kim 2018: biofilm acidogenicity/saliva) vs No competing model

Model discrimination (area under the ROC curve, AUC) · Children and adolescents aged 1-18 years

Simplified childhood caries prediction models show moderate pooled discrimination (AUC 0.79, 95% CI 0.73-0.84) but with very high heterogeneity (I2=97.3%) and all models at high risk of bias (PROBAST); ungraded.

1 finding from 1 review

Living with HIV and undergoing antiretroviral therapy (ART/HAART) vs Healthy HIV-negative controls

Poor (inadequate) oral hygiene (prevalence) · Children or adolescents

No significant difference in oral hygiene between CLWH on ART and healthy controls (OR 1.23, 95% CI 0.73 to 2.07; single study).

1 finding from 1 review

Clear aligners (Invisalign / thermoformed aligners) vs Fixed appliances

Gingival inflammation-related index · Adolescents/teenagers undergoing orthodontic treatment

A single study reported lower simplified gingival index with aligners versus fixed appliances in adolescents at 1 month (MD -8.46, 95% CI -10.47 to -6.45; ungraded).

1 finding from 1 review

Clear aligners (Invisalign / thermoformed aligners) vs Fixed appliances

Plaque · Adolescents/teenagers undergoing orthodontic treatment

A single study reported lower simplified plaque index with aligners versus fixed appliances in adolescents at 1 month (MD -14.78, 95% CI -16.74 to -12.82; ungraded).

1 finding from 1 review