Findings

What do systematic reviews say?

7 questions · 7 findings · 1 reviews · Musculoskeletal

No studies found 4 · 57.1%GRADE not reported 0 · 0%Very low 0 · 0%Low 3 · 42.9%Moderate 0 · 0%High 0 · 0%

Functional disability at 3 months ‐ not measured · acute gout

The review found no eligible studies for this question.

1 finding from 1 review

Interleukin‐1 inhibitors for acute gout 2014 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Health‐related quality of life ‐ not measured · acute gout

The review found no eligible studies for this question.

1 finding from 1 review

Interleukin‐1 inhibitors for acute gout 2014 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Participant global assessment of success Not measured · acute gout

The review found no eligible studies for this question.

1 finding from 1 review

Interleukin‐1 inhibitors for acute gout 2014 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Withdrawals due to adverse events · acute gout

Rilonacept showed no clear difference in adverse events ‐ study withdrawals due to adverse events compared with indomethacin (low certainty).

1 finding from 1 review

Interleukin‐1 inhibitors for acute gout 2014 · Cochrane Headline outcomes only
RR 0.51 [0.05, 5.47]
1 study · 151 participants
Low

Adverse events as N of participants with at least one adverse event objective · acute gout

Rilonacept showed no clear difference in adverse events ‐ participants with at least 1 adverse event compared with indomethacin (low certainty).

1 finding from 1 review

Interleukin‐1 inhibitors for acute gout 2014 · Cochrane Headline outcomes only
RR 1.19 [0.75, 1.88]
1 study · 151 participants
Low

Pain ‐ change from baseline to 24 to 72 hours Assessed on numerical rating scale (0 = no pain; 10 = extreme pain) · acute gout

1 finding from 1 review

Interleukin‐1 inhibitors for acute gout 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 148 participants
Low

Inflammation ‐ not measured · acute gout

The review found no eligible studies for this question.

1 finding from 1 review

Interleukin‐1 inhibitors for acute gout 2014 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found