Findings

What do systematic reviews say?

6 questions · 6 findings · 3 reviews · Oral medicine and oral cancer

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No studies found 0 · 0%GRADE not reported 5 · 83.3%Very low 1 · 16.7%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Povidone vs Water

Oral mucositis (any severity) · Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies

1 finding from 1 review

Interventions for preventing oral mucositis for patients with cancer receiving treatment 2011 · Cochrane All outcomes
Median 28 days
no estimate extracted
2 studies
GRADE not reported

Subgingival laser irradiation + povidone-iodine vs SRP

Volatile sulphur compounds (VSC), halimeter · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced or physiological…

Subgingival laser irradiation + povidone-iodine led to higher volatile sulphur compounds (VSC) compared with SRP alone; GRADE not reported.

1 finding from 1 review

Interventions for managing halitosis 2019 · Cochrane All outcomes
4 weeks
MD 70.0 [63.88, 76.12]
1 study · 40 participants
GRADE not reported

Subgingival laser irradiation + povidone-iodine vs SRP

Dentist-reported organoleptic test (OLT) score (scale 0 to 5) · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced or physiological…

It is very uncertain whether subgingival laser irradiation + povidone-iodine changes dentist-reported organoleptic test (OLT) score (scale 0 to 5) compared with SRP alone (very low certainty).

1 finding from 1 review

Interventions for managing halitosis 2019 · Cochrane All outcomes
mean 4 weeks
MD 0.49 [0.3, 0.68]
1 study · 40 participants
Very low

Low‐level laser therapy vs Povidone

Oral mucositis (moderate to severe) · Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies

Laser (low level) led to lower oral mucositis (moderate to severe) compared with povidone; GRADE not reported.

1 finding from 1 review

Interventions for preventing oral mucositis for patients with cancer receiving treatment 2011 · Cochrane All outcomes
Median 28 days
RR 0.29 [0.16, 0.54]
1 study · 50 participants
GRADE not reported

Low‐level laser therapy vs Povidone

Oral mucositis (severe) · Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies

Laser (low level) led to lower oral mucositis (severe) compared with povidone; GRADE not reported.

1 finding from 1 review

Interventions for preventing oral mucositis for patients with cancer receiving treatment 2011 · Cochrane All outcomes
Median 28 days
RR 0.02 [0, 0.31]
1 study · 50 participants
GRADE not reported

GM-CSF vs povidone‐iodine

Time to heal mucositis (days) · People with cancer receiving chemotherapy or radiotherapy (or both) who have oral mucositis

Granulocyte macrophage-colony stimulating factor (GM-CSF) led to lower time to heal mucositis (days) compared with povidone iodine; GRADE not reported.

1 finding from 1 review

Interventions for treating oral mucositis for patients with cancer receiving treatment 2010 · Cochrane All outcomes
MD -3.50 [-4.14, -2.86]
1 study · 31 participants
GRADE not reported