Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

69 questions · 69 findings · 7 reviews

No studies found 15 · 21.7%GRADE not reported 5 · 7.2%Very low 21 · 30.4%Low 15 · 21.7%Moderate 10 · 14.5%High 3 · 4.3%

Plasma exchange vs sham exchange or supportive treatment

Recurrence of hyperthyroidism (relapse) [measured by serum thyroid hormone levels above the normal range after withdrawal of methimazole or end of radioiodine treatment] · patients with Guillain‐Barré syndrome

Plasma exchange probably leads to higher relapses at 1 year compared with sham exchange or supportive treatment (moderate certainty).

1 finding from 1 review

Cerebrospinal fluid filtration vs plasma exchange

Improvement in disability grade Defined as achievement of a specified degree of improvement · patients with Guillain‐Barré syndrome

It is very uncertain whether cerebrospinal fluid filtration changes improvement in disability grade Defined as achievement of a… compared with plasma exchange (very low certainty).

1 finding from 1 review