Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

84 questions · 84 findings · 4 reviews · Neuromuscular · Headline outcomes only

No studies found 15 · 17.9%GRADE not reported 2 · 2.4%Very low 41 · 48.8%Low 23 · 27.4%Moderate 3 · 3.6%High 0 · 0%

Brain‐derived neurotrophic factor vs placebo

Death or disability after 12 months · patients with Guillain‐Barré syndrome

It is very uncertain whether brain‐derived neurotrophic factor changes death or disability after 12 months compared with placebo (very low certainty).

1 finding from 1 review

Brain‐derived neurotrophic factor vs placebo

Participants with 1 or more serious adverse events · patients with Guillain‐Barré syndrome

It is very uncertain whether brain‐derived neurotrophic factor changes participants with 1 or more serious adverse events compared with placebo (very low certainty).

1 finding from 1 review

Cerebrospinal fluid filtration vs plasma exchange

Improvement in disability grade Defined as achievement of a specified degree of improvement · patients with Guillain‐Barré syndrome

It is very uncertain whether cerebrospinal fluid filtration changes improvement in disability grade Defined as achievement of a… compared with plasma exchange (very low certainty).

1 finding from 1 review

Interferon beta‐1a vs placebo

Improvement in disability grade Defined as achievement of a specified degree of improvement · patients with Guillain‐Barré syndrome

It is very uncertain whether interferon beta‐1a changes improvement in disability grade Defined as achievement of a… compared with placebo (very low certainty).

1 finding from 1 review

Cerebrospinal fluid filtration vs plasma exchange

Participants with 1 or more serious adverse events · patients with Guillain‐Barré syndrome

It is very uncertain whether cerebrospinal fluid filtration changes participants with 1 or more serious adverse events compared with plasma exchange (very low certainty).

1 finding from 1 review

Tripterygium polyglycoside vs corticosteroids

Improvement in disability grade Defined as achievement of a specified degree of improvement · patients with Guillain‐Barré syndrome

It is very uncertain whether tripterygium polyglycoside changes improvement in disability grade Defined as achievement of a… compared with corticosteroids (very low certainty).

1 finding from 1 review