Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

11 questions · 11 findings · 2 reviews · Oral Health

No studies found 2 · 18.2%GRADE not reported 9 · 81.8%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Clotrimazole 50 mg (partially absorbed) vs Clotrimazole 10 mg (partially absorbed)

Clinical: eradication of oral candidiasis · Patients with cancer receiving chemotherapy and/or radiotherapy with overt oral candidiasis

Clotrimazole 50 mg (partially absorbed) showed no clear difference in clinical: eradication of oral candidiasis compared with clotrimazole 10 mg (partially absorbed); GRADE not reported.

1 finding from 1 review

Clotrimazole 50 mg (partially absorbed) vs Clotrimazole 10 mg (partially absorbed)

Mycological: eradication of oral candidiasis · Patients with cancer receiving chemotherapy and/or radiotherapy with overt oral candidiasis

Clotrimazole 50 mg (partially absorbed) led to higher mycological: eradication of oral candidiasis compared with clotrimazole 10 mg (partially absorbed); GRADE not reported.

1 finding from 1 review

Miconazole 50 mg tablet (partially absorbed) vs Miconazole 500 mg gel (partially absorbed)

Clinical: eradication of oral candidiasis · Patients with cancer receiving chemotherapy and/or radiotherapy with overt oral candidiasis

Miconazole 50 mg tablet (partially absorbed) showed no clear difference in clinical: eradication of oral candidiasis compared with miconazole 500 mg gel (partially absorbed); GRADE not reported.

1 finding from 1 review

Clotrimazole (partially absorbed from GI tract) vs placebo

Mycological: eradication of oral candidiasis · Patients with cancer receiving chemotherapy and/or radiotherapy with overt oral candidiasis

Clotrimazole (partially absorbed from GI tract) showed no clear difference in mycological: eradication of oral candidiasis compared with placebo; GRADE not reported.

1 finding from 1 review

Clotrimazole (partially absorbed from GI tract) vs placebo

Clinical: eradication of oral candidiasis · Patients with cancer receiving chemotherapy and/or radiotherapy with overt oral candidiasis

Clotrimazole (partially absorbed from GI tract) showed no clear difference in clinical: eradication of oral candidiasis compared with placebo; GRADE not reported.

1 finding from 1 review

Antifungal drugs partially absorbed from GI tract (miconazole, clotrimazole) vs placebo or no treatment

Oral candidiasis (present) · Patients with cancer receiving chemotherapy and/or radiotherapy

Antifungal drugs partially absorbed from GI tract (miconazole,… led to lower oral candidiasis (present) compared with placebo or no treatment; GRADE not reported.

1 finding from 1 review

Antifungal drugs partially absorbed from GI tract (miconazole, clotrimazole) vs placebo or no treatment

Empirical antifungal treatment · Patients with cancer receiving chemotherapy and/or radiotherapy

Antifungal drugs partially absorbed from GI tract (miconazole,… showed no clear difference in empirical antifungal treatment compared with placebo or no treatment; GRADE not reported.

1 finding from 1 review

Partially absorbed antifungal drug (e.g., clotrimazole, miconazole) vs Drug not absorbed from GI tract (e.g., nystatin, amphotericin B)

Outcome not reported · Patients with cancer receiving chemotherapy and/or radiotherapy with overt oral candidiasis

The review found no eligible studies for this question.

1 finding from 1 review

Partially absorbed antifungal drug (e.g., clotrimazole, miconazole) vs Absorbed antifungal drug (e.g., fluconazole, ketoconazole, itraconazole)

Outcome not reported · Patients with cancer receiving chemotherapy and/or radiotherapy with overt oral candidiasis

The review found no eligible studies for this question.

1 finding from 1 review

Antifungal drugs partially absorbed from GI tract (miconazole, clotrimazole) vs placebo or no treatment

Systemic fungal infection · Patients with cancer receiving chemotherapy and/or radiotherapy

Antifungal drugs partially absorbed from GI tract (miconazole,… showed no clear difference in systemic fungal infection compared with placebo or no treatment; GRADE not reported.

1 finding from 1 review