Orexin antagonists vs placebo
Change from baseline in total nocturnal sleep time · sleep disturbances in dementia
1 finding from 1 review
- no estimate extracted1 study · 274 participantsModerate
Findings
What do systematic reviews say?
7 questions · 7 findings · 1 reviews
No studies found 2 · 28.6%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 5 · 71.4%High 0 · 0%
Orexin antagonists vs placebo
Consolidated sleep time · sleep disturbances in dementia
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Orexin antagonists vs placebo
Change from baseline in ratio of number of nocturnal awakenings to total sleep time × 100 · sleep disturbances in dementia
1 finding from 1 review
- no estimate extracted1 study · 274 participantsModerate
Orexin antagonists vs placebo
Number of participants reporting an adverse event · sleep disturbances in dementia
Orexin antagonists showed no clear difference in reporting ≥ 1 adverse event compared with placebo (moderate certainty).
1 finding from 1 review
- RR 1.29 [0.83, 1.99]2 studies · 323 participantsModerate
Orexin antagonists vs placebo
Cognitive function · sleep disturbances in dementia
1 finding from 1 review
- no estimate extracted1 study · 274 participantsModerate
Orexin antagonists vs placebo
Quality of life · sleep disturbances in dementia
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Orexin antagonists vs placebo
Change from baseline in carer distress · sleep disturbances in dementia
1 finding from 1 review
- no estimate extracted1 study · 274 participantsModerate