Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

27 questions · 27 findings · 2 reviews · Common Mental Disorders

No studies found 14 · 51.9%GRADE not reported 0 · 0%Very low 8 · 29.6%Low 5 · 18.5%Moderate 0 · 0%High 0 · 0%

Opioid antagonists vs placebo

Treatment responseaClinical Global Impressions ‐ Improvement Scale (CGI‐I) (no. of responders) & NIMH Trichotillomania Severity Scale (NIMH‐TSS) (no. of responders as > 50% reduction) · adults with trichotillomania

It is very uncertain whether opioid antagonists changes treatment responseaClinical Global Impressions ‐ Improvement Scale… compared with placebo (very low certainty).

1 finding from 1 review