Findings

What do systematic reviews say?

24 questions · 25 findings · 4 reviews · Neuromuscular

Sort:Best matchNewest Highest certainty Download CSV

No studies found 5 · 20%GRADE not reported 0 · 0%Very low 11 · 44%Low 7 · 28%Moderate 2 · 8%High 0 · 0%

Ascorbic acid vs placebo

Health‐related quality of life (physical) · people with fatigue in peripheral neuropathy

1 finding from 1 review

Interventions for fatigue in peripheral neuropathy 2014 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 400 participants
Moderate

Ascorbic acid vs placebo

Health‐related quality of life (mental) · people with fatigue in peripheral neuropathy

1 finding from 1 review

Interventions for fatigue in peripheral neuropathy 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 123 participants
Moderate

Eplerenone (25 mg daily) vs placebo

Change in cardiac function: change (decline) from baseline in left ventricular strain · boys with DMD and left ventricular ejection fraction 45% or more

1 finding from 1 review

Interventions for preventing and treating cardiac complications in Duchenne and Becker muscular dystrophy and X‐linked… 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 42 participants
Very low

Eplerenone (25 mg daily) vs placebo

Change in Ejection fraction (%) · boys with DMD and left ventricular ejection fraction 45% or more

1 finding from 1 review

Interventions for preventing and treating cardiac complications in Duchenne and Becker muscular dystrophy and X‐linked… 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 42 participants
Very low

Eplerenone (25 mg daily) vs placebo

Size of metabolically abnormal areas of myocardium · boys with DMD and left ventricular ejection fraction 45% or more

1 finding from 1 review

Interventions for preventing and treating cardiac complications in Duchenne and Becker muscular dystrophy and X‐linked… 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 42 participants
Low

Eplerenone (25 mg daily) vs placebo

Improvements in quality of life measures · boys with DMD and left ventricular ejection fraction 45% or more

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for preventing and treating cardiac complications in Duchenne and Becker muscular dystrophy and X‐linked… 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Eplerenone (25 mg daily) vs placebo

Adverse events · boys with DMD and left ventricular ejection fraction 45% or more

It is very uncertain whether eplerenone (25 mg daily) changes adverse events compared with placebo (very low certainty).

1 finding from 1 review

Interventions for preventing and treating cardiac complications in Duchenne and Becker muscular dystrophy and X‐linked… 2018 · Cochrane Headline outcomes only
RR 0.37 [0.02, 8.48]
1 study · 42 participants
Very low

Idebenone vs placebo

Change in Ejection fraction (%) · boys (aged 8 to 16 years old) with subclinical cardiomyopathy in DMD

1 finding from 1 review

Interventions for preventing and treating cardiac complications in Duchenne and Becker muscular dystrophy and X‐linked… 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 21 participants
Very low

Idebenone vs placebo

Change in cardiac function (change in peak systolic radial strain in LV lateral wall segments) · boys (aged 8 to 16 years old) with subclinical cardiomyopathy in DMD

1 finding from 1 review

Interventions for preventing and treating cardiac complications in Duchenne and Becker muscular dystrophy and X‐linked… 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 18 participants
Very low

Idebenone vs placebo

Change in cardiac function (change in systolic radial strain rate LV inferolateral wall) · boys (aged 8 to 16 years old) with subclinical cardiomyopathy in DMD

1 finding from 1 review

Interventions for preventing and treating cardiac complications in Duchenne and Becker muscular dystrophy and X‐linked… 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 18 participants
Very low

Idebenone vs placebo

Size of metabolically abnormal areas of myocardium · boys (aged 8 to 16 years old) with subclinical cardiomyopathy in DMD

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for preventing and treating cardiac complications in Duchenne and Becker muscular dystrophy and X‐linked… 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Idebenone vs placebo

Improvements in quality of life measures · boys (aged 8 to 16 years old) with subclinical cardiomyopathy in DMD

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for preventing and treating cardiac complications in Duchenne and Becker muscular dystrophy and X‐linked… 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Idebenone vs placebo

Adverse events · boys (aged 8 to 16 years old) with subclinical cardiomyopathy in DMD

1 finding from 1 review

Interventions for preventing and treating cardiac complications in Duchenne and Becker muscular dystrophy and X‐linked… 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 21 participants
Low

Idebenone vs placebo

Change in cardiac function (change in fractional shortening) · boys (aged 8 to 16 years old) with subclinical cardiomyopathy in DMD

1 finding from 1 review

Interventions for preventing and treating cardiac complications in Duchenne and Becker muscular dystrophy and X‐linked… 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 21 participants
Very low

Growth hormone (0.23 mg/kg/week for DMD and 0.07 mg/kg/week in BMD SC injection) vs placebo

Change in Ejection fraction (%) · people with DMD or BMD (ages not stated)

1 finding from 1 review

Interventions for preventing and treating cardiac complications in Duchenne and Becker muscular dystrophy and X‐linked… 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 16 participants
Very low

Growth hormone (0.23 mg/kg/week for DMD and 0.07 mg/kg/week in BMD SC injection) vs placebo

Size of metabolically abnormal areas of myocardium · people with DMD or BMD (ages not stated)

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for preventing and treating cardiac complications in Duchenne and Becker muscular dystrophy and X‐linked… 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Growth hormone (0.23 mg/kg/week for DMD and 0.07 mg/kg/week in BMD SC injection) vs placebo

Improvements in quality of life measures · people with DMD or BMD (ages not stated)

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for preventing and treating cardiac complications in Duchenne and Becker muscular dystrophy and X‐linked… 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Growth hormone (0.23 mg/kg/week for DMD and 0.07 mg/kg/week in BMD SC injection) vs placebo

Adverse events · people with DMD or BMD (ages not stated)

1 finding from 1 review

Interventions for preventing and treating cardiac complications in Duchenne and Becker muscular dystrophy and X‐linked… 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 16 participants
Very low

Surgery for Bell's palsy vs medical treatment (oral prednisolone) or no treatment

Complete recovery of facial nerve function at 12 months Defined as: complete recovery HB grade I. · Bell's palsy

It is very uncertain whether surgery for Bell's palsy changes complete recovery of facial nerve function at 12 months Defined as:… compared with medical treatment (oral prednisolone) or no treatment (very low certainty).

1 finding from 1 review

Surgical interventions for the early management of Bell's palsy 2021 · Cochrane Headline outcomes only
RR 0.76
2 studies · 57 participants
Very low

Surgery for Bell's palsy vs medical treatment (oral prednisolone) or no treatment

Complications and side effects · Bell's palsy

It is very uncertain whether surgery for Bell's palsy changes side effects and complications of treatmentMeasured by clinical… compared with medical treatment (oral prednisolone) or no treatment (very low certainty).

1 finding from 1 review

Surgical interventions for the early management of Bell's palsy 2021 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 57 participants
Very low