Findings

What do systematic reviews say?

5 questions · 5 findings · 1 reviews · Multiple Sclerosis and Rare Diseases of the CNS

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 3 · 60%Moderate 2 · 40%High 0 · 0%

SAEs · people with multiple sclerosis

Omega‐3 showed no clear difference in SAEs (assessed as number of participants experiencing a SAE) compared with omega‐6 (low certainty).

1 finding from 1 review

Dietary interventions for multiple sclerosis‐related outcomes 2020 · Cochrane Headline outcomes only
RR 1.12 [0.38, 3.31]
4 studies · 230 participants
Low

Relapse · people with multiple sclerosis

Omega‐3 showed no clear difference in relapse(assessed as number of participants experiencing relapse) compared with omega‐6 (low certainty).

1 finding from 1 review

Dietary interventions for multiple sclerosis‐related outcomes 2020 · Cochrane Headline outcomes only
RR 1.02 [0.62, 1.66]
2 studies · 129 participants
Low

Change in validated disability scale ( · people with multiple sclerosis

1 finding from 1 review

Dietary interventions for multiple sclerosis‐related outcomes 2020 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 166 participants
Low

Global impression of deterioration (investigator defined global impression of deterioration) · people with multiple sclerosis

Omega‐3 showed no clear difference in global impression of deterioration (investigator defined global… compared with omega‐6 (moderate certainty).

1 finding from 1 review

Dietary interventions for multiple sclerosis‐related outcomes 2020 · Cochrane Headline outcomes only
RR 0.99 [0.51, 1.91]
1 study · 86 participants
Moderate

MRI activity(assessed by new gadolinium‐enhancing lesions) · people with multiple sclerosis

1 finding from 1 review

Dietary interventions for multiple sclerosis‐related outcomes 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 86 participants
Moderate