Findings

What do systematic reviews say?

12 questions · 12 findings · 1 reviews

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No studies found 1 · 8.3%GRADE not reported 0 · 0%Very low 0 · 0%Low 11 · 91.7%Moderate 0 · 0%High 0 · 0%

Oestrogen cream vs other regimens

Improvement in symptoms (participant‐assessed) (oestrogen cream vs isoflavone gel) · postmenopausal women with vaginal atrophy

Oestrogen cream showed no clear difference in improvement in symptoms (participant‐assessed) (oestrogen cream vs… compared with other regimens (low certainty).

1 finding from 1 review

Local oestrogen for vaginal atrophy in postmenopausal women 2016 · Cochrane Headline outcomes only
OR 2.08 [0.08, 53.76]
1 study · 50 participants
Low

Oestrogen cream vs other regimens

Improvement in symptoms (participant‐assessed) oestrogen cream vs placebo) · postmenopausal women with vaginal atrophy

Oestrogen cream may leads to higher improvement in symptoms (participant‐assessed) oestrogen cream vs… compared with other regimens (low certainty).

1 finding from 1 review

Local oestrogen for vaginal atrophy in postmenopausal women 2016 · Cochrane Headline outcomes only
OR 4.1 [1.88, 8.93]
2 studies · 198 participants
Low

Oestrogen cream vs other regimens

Improvement in symptoms (clinician‐assessed) (oestrogen cream vs placebo) · postmenopausal women with vaginal atrophy

Oestrogen cream may leads to higher improvement in symptoms (clinician‐assessed) (oestrogen cream vs… compared with other regimens (low certainty).

1 finding from 1 review

Local oestrogen for vaginal atrophy in postmenopausal women 2016 · Cochrane Headline outcomes only
OR 3.29 [1.47, 7.36]
1 study · 153 participants
Low

Oestrogen cream vs other regimens

Adverse events (total adverse events) (oestrogen cream vs non‐hormonal lubricant gel) · postmenopausal women with vaginal atrophy

Oestrogen cream showed no clear difference in adverse events (total adverse events) (oestrogen cream vs… compared with other regimens (low certainty).

1 finding from 1 review

Local oestrogen for vaginal atrophy in postmenopausal women 2016 · Cochrane Headline outcomes only
OR 10.67 [0.54, 209.64]
1 study · 50 participants
Low

Oestrogen ring vs other regimens

Improvement in symptoms (participant‐assessed) (oestrogen ring vs oestrogen cream) · postmenopausal women with vaginal atrophy

Oestrogen ring showed no clear difference in improvement in symptoms (participant‐assessed) (oestrogen ring vs… compared with other regimens (low certainty).

1 finding from 1 review

Local oestrogen for vaginal atrophy in postmenopausal women 2016 · Cochrane Headline outcomes only
OR 1.33 [0.8, 2.19]
2 studies · 341 participants
Low

Oestrogen ring vs other regimens

Endometrial thickness (mm) · postmenopausal women with vaginal atrophy

Oestrogen ring may leads to lower endometrial thickness (oestrogen ring vs oestrogen cream) compared with other regimens (low certainty).

1 finding from 1 review

Local oestrogen for vaginal atrophy in postmenopausal women 2016 · Cochrane Headline outcomes only
OR 0.36 [0.14, 0.94]
2 studies · 273 participants
Low

Oestrogen ring vs other regimens

Improvement in symptoms (clinician‐assessed) (oestrogen ring vs oestrogen cream) · postmenopausal women with vaginal atrophy

Oestrogen ring showed no clear difference in improvement in symptoms (clinician‐assessed) (oestrogen ring vs… compared with other regimens (low certainty).

1 finding from 1 review

Local oestrogen for vaginal atrophy in postmenopausal women 2016 · Cochrane Headline outcomes only
OR 1.04 [0.7, 1.53]
3 studies · 533 participants
Low

Oestrogen ring vs other regimens

Adverse events (total adverse events) (oestrogen ring vs oestrogen cream) · postmenopausal women with vaginal atrophy

Oestrogen ring showed no clear difference in adverse events (total adverse events) (oestrogen ring vs oestrogen… compared with other regimens (low certainty).

1 finding from 1 review

Local oestrogen for vaginal atrophy in postmenopausal women 2016 · Cochrane Headline outcomes only
OR 0.88 [0.47, 1.63]
1 study · 192 participants
Low

Oestrogen tablets vs other regimens

Endometrial thickness (mm) · postmenopausal women with vaginal atrophy

Oestrogen tablets showed no clear difference in endometrial thickness (oestrogen tablets vs oestrogen cream) compared with other regimens (low certainty).

1 finding from 1 review

Local oestrogen for vaginal atrophy in postmenopausal women 2016 · Cochrane Headline outcomes only
OR 0.31 [0.06, 1.6]
2 studies · 151 participants
Low

Oestrogen tablets vs other regimens

Improvement in symptoms (clinician‐assessed) (oestrogen tablets vs oestrogen cream) · postmenopausal women with vaginal atrophy

Oestrogen tablets showed no clear difference in improvement in symptoms (clinician‐assessed) (oestrogen tablets vs… compared with other regimens (low certainty).

1 finding from 1 review

Local oestrogen for vaginal atrophy in postmenopausal women 2016 · Cochrane Headline outcomes only
OR 1.03 [0.7, 1.52]
3 studies · 528 participants
Low

Oestrogen tablets vs other regimens

Improvement in symptoms (participant‐assessed) (oestrogen cream vs isoflavone gel) · postmenopausal women with vaginal atrophy

Oestrogen tablets showed no clear difference in improvement in symptoms (participant‐assessed) (oestrogen tablets vs… compared with other regimens (low certainty).

1 finding from 1 review

Local oestrogen for vaginal atrophy in postmenopausal women 2016 · Cochrane Headline outcomes only
OR 1.06 [0.55, 2.01]
2 studies · 208 participants
Low

Oestrogen cream vs other regimens

Endometrial thickness not reported · postmenopausal women with vaginal atrophy

The review found no eligible studies for this question.

1 finding from 1 review

Local oestrogen for vaginal atrophy in postmenopausal women 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found