What do systematic reviews say?

Noradrenaline reuptake inhibitors vs placebo

It is very uncertain whether noradrenaline reuptake inhibitors changes mental state: significant response or improvement in negative… compared with placebo (very low certainty).

• Selective noradrenaline reuptake inhibitors for schizophrenia 2018 · Cochrane Headline outcomes only
  RR 3.17 [1.52, 6.58]
  1 study · 50 participants
  Very low

Noradrenaline reuptake inhibitors vs placebo

• Selective noradrenaline reuptake inhibitors for schizophrenia 2018 · Cochrane Headline outcomes only
  no estimate extracted
  5 studies · 294 participants
  Low

Noradrenaline reuptake inhibitors vs placebo

It is very uncertain whether noradrenaline reuptake inhibitors changes clinical global response: significant response or improvement in… compared with placebo (very low certainty).

• Selective noradrenaline reuptake inhibitors for schizophrenia 2018 · Cochrane Headline outcomes only
  RR 0.99 [0.45, 2.2]
  1 study · 28 participants
  Very low

Noradrenaline reuptake inhibitors vs placebo

The review found no eligible studies for this question.

• Selective noradrenaline reuptake inhibitors for schizophrenia 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Noradrenaline reuptake inhibitors vs placebo

• Selective noradrenaline reuptake inhibitors for schizophrenia 2018 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 180 participants
  Low

Noradrenaline reuptake inhibitors vs placebo

• Selective noradrenaline reuptake inhibitors for schizophrenia 2018 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 114 participants
  Very low

Noradrenaline reuptake inhibitors vs placebo

Noradrenaline reuptake inhibitors showed no clear difference in adverse effects: Nausea ‐ short term (2 to 12 weeks) compared with placebo (low certainty).

• Selective noradrenaline reuptake inhibitors for schizophrenia 2018 · Cochrane Headline outcomes only
  RR 0.49 [0.1, 2.41]
  3 studies · 176 participants
  Low