Restoration survival · Primary posterior teeth with multiple-surface cavities
Multiple-surface high-viscosity glass-ionomer ART restorations in primary teeth had moderate 2-year survival (62%, 95% CI 51-73%); evidence ungraded.
3 findings from 1 review
Restoration survival · Permanent posterior teeth with multiple-surface cavities
Multiple-surface high-viscosity glass-ionomer ART restorations in permanent teeth had high 1-year survival (86%, 95% CI 59-98%); evidence ungraded.
3 findings from 1 review
Dental caries · Individuals assessed for dental caries (cases with caries/high caries vs. caries-free or low/very-low-caries controls)
A gene-based analysis indicated that multiple LTF variants were jointly associated with dental caries risk (weighted TPM P = 0.0007; no pooled effect estimate; ungraded).
1 finding from 1 review
Diagnostic odds ratio (DOR) by subgroup: Multiple sites per tooth (detection of early enamel caries, D1 threshold) · Asymptomatic children, adolescents, or adults presenting for clinical examination (in vivo studies), or extracted teeth of children or…
1 finding from 1 review
Post-treatment pain within 1 week (from first session) · People aged 10 years or above requiring root canal treatment; permanent teeth with completely formed apex and without internal resorption
Single-visit root canal treatment probably leads to higher post-treatment pain within 1 week (from first session) compared with multiple-visit root canal treatment (two or more visits) (moderate certainty).
1 finding from 1 review
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · People aged 10 years or above requiring root canal treatment; permanent teeth with completely formed apex and without internal resorption
Single-visit root canal treatment showed no clear difference in postoperative pain in the immediate postobturation period (up to 72… compared with multiple-visit root canal treatment (two or more visits) (low certainty).
1 finding from 1 review
Tooth extraction due to endodontic problems · People aged 10 years or above requiring root canal treatment; permanent teeth with completely formed apex and without internal resorption
It is very uncertain whether single-visit root canal treatment changes tooth extraction due to endodontic problems compared with multiple-visit root canal treatment (two or more visits) (very low certainty).
1 finding from 1 review
Swelling or flare-up · People aged 10 years or above requiring root canal treatment; permanent teeth with completely formed apex and without internal resorption
It is very uncertain whether single-visit root canal treatment changes swelling or flare-up compared with multiple-visit root canal treatment (two or more visits) (very low certainty).
1 finding from 1 review
Analgesic (painkiller) use · People aged 10 years or above requiring root canal treatment; permanent teeth with completely formed apex and without internal resorption
It is very uncertain whether single-visit root canal treatment changes analgesic (painkiller) use compared with multiple-visit root canal treatment (two or more visits) (very low certainty).
1 finding from 1 review
Pain at two weeks (postobturation) · People aged 10 years or above requiring root canal treatment; permanent teeth with completely formed apex and without internal resorption
Single-visit root canal treatment showed no clear difference in pain at two weeks (postobturation) compared with multiple-visit root canal treatment (two or more visits); GRADE not reported.
1 finding from 1 review
Pain at 12 months or more (long-term postobturation pain) · People aged 10 years or above requiring root canal treatment; permanent teeth with completely formed apex and without internal resorption
1 finding from 1 review
Sinus or fistula formation at last · People aged 10 years or above requiring root canal treatment; permanent teeth with completely formed apex and without internal resorption
It is very uncertain whether single-visit root canal treatment changes sinus tract or fistula formation compared with multiple-visit root canal treatment (two or more visits) (very low certainty).
1 finding from 1 review
Postoperative pain intensity in the immediate postobturation period (up to 72 hours), continuous (VAS) · People aged 10 years or above requiring root canal treatment; permanent teeth with completely formed apex and without internal resorption
Single-visit root canal treatment showed no clear difference in postoperative pain intensity in the immediate postobturation period… compared with multiple-visit root canal treatment (two or more visits) (low certainty).
1 finding from 1 review
Pain at 1 month · People aged 10 years or above requiring root canal treatment; permanent teeth with completely formed apex and without internal resorption
1 finding from 1 review
One study (Dhyani 2022) reported pain at 1 month: 60 teeth (all vital at enrolment, mechanical NiTi), 0 events (no participant reported pain at 1 month); no meta-analysis
1 study · 60 participants
GRADE not reported
Postobturation pain at 1 week · People aged 10 years or above requiring root canal treatment; permanent teeth with completely formed apex and without internal resorption
It is very uncertain whether single-visit root canal treatment changes postobturation pain at 1 week compared with multiple-visit root canal treatment (two or more visits) (very low certainty).
1 finding from 1 review
Radiological failure (periapical radiolucency) after at least 1 year · People aged 10 years or above requiring root canal treatment; permanent teeth with completely formed apex and without internal resorption
Single-visit root canal treatment showed no clear difference in radiological failure (periapical radiolucency) after at least 1 year compared with multiple-visit root canal treatment (two or more visits) (moderate certainty).
1 finding from 1 review
Keratinized tissue width change · Adult patients with multiple recession-type defects (Miller Class I/II, at least 3 mm)
PRF + CAF showed no clear difference in keratinized tissue width change compared with SCTG + CAF; GRADE not reported.
1 finding from 1 review
MD -0.26 [-0.98, 0.45]
2 studies
GRADE not reported
Occurrence of adverse effects or postoperative complications · Adult patients with multiple recession-type defects (Miller Class I/II, at least 3 mm)
1 finding from 1 review
Aesthetic condition change related to patient's opinion · Adult patients with multiple recession-type defects (Miller Class I/II, at least 3 mm)
The review found no eligible studies for this question.
1 finding from 1 review
Attachment change · Adult patients with multiple recession-type defects (Miller Class I/II, at least 3 mm)
PRF + CAF led to lower clinical attachment level change compared with SCTG + CAF; GRADE not reported.
1 finding from 1 review
MD -0.37 [-0.69, -0.06]
2 studies
GRADE not reported