Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

29 questions · 29 findings · 2 reviews · Airways

No studies found 13 · 44.8%GRADE not reported 0 · 0%Very low 0 · 0%Low 9 · 31%Moderate 7 · 24.1%High 0 · 0%

Bromhexine vs placebo

Frequency and duration of exacerbations · people with bronchiectasis

The review found no eligible studies for this question.

1 finding from 1 review

RhDNase vs placebo

Adverse events · people with bronchiectasis

The review found no eligible studies for this question.

1 finding from 1 review

RhDNase vs placebo

Health‐related quality of life · people with bronchiectasis

The review found no eligible studies for this question.

1 finding from 1 review

RhDNase vs placebo

Symptoms sputum colour Scale used not reported · people with bronchiectasis

RhDNase showed no clear difference in symptoms sputum colour Scale used not reported compared with placebo (low certainty).

1 finding from 1 review

RhDNase vs placebo

Deaths · people with bronchiectasis

RhDNase showed no clear difference in deaths compared with placebo (low certainty).

1 finding from 1 review

RhDNase vs placebo

Lung function: FEV1 mL (percentage change from baseline) · people with bronchiectasis

RhDNase showed no clear difference in lung function % change FEV1 compared with placebo (low certainty).

1 finding from 1 review

Erdosteine vs no treatment

Frequency and duration of exacerbations · people with bronchiectasis

The review found no eligible studies for this question.

1 finding from 1 review

Erdosteine vs no treatment

Hospitalisations for infective exacerbations · people with bronchiectasis

The review found no eligible studies for this question.

1 finding from 1 review

Erdosteine vs no treatment

Health‐related quality of life · people with bronchiectasis

The review found no eligible studies for this question.

1 finding from 1 review

Erdosteine vs no treatment

Symptoms mucus volume production · people with bronchiectasis

Erdosteine showed no clear difference in symptoms mucus volume production compared with no treatment (low certainty).

1 finding from 1 review

Bromhexine vs placebo

Hospital admissions · people with bronchiectasis

The review found no eligible studies for this question.

1 finding from 1 review