Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

8 questions · 8 findings · 2 reviews · Other oral health

No studies found 5 · 62.5%GRADE not reported 3 · 37.5%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Cognitive behaviour therapy vs Attention placebo

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · Adults over 18 years of age with chronic orofacial pain (burning mouth syndrome)

Cognitive (behavioural) therapy led to lower burning mouth pain intensity (6-month follow-up) compared with attention placebo; GRADE not reported.

1 finding from 1 review

Cognitive behaviour therapy vs Attention placebo

Burning mouth pain intensity (post-treatment) · Adults over 18 years of age with chronic orofacial pain (burning mouth syndrome)

Cognitive (behavioural) therapy led to lower burning mouth pain intensity (post-treatment) compared with attention placebo; GRADE not reported.

1 finding from 1 review

Antiseptic mouthwash (e.g. chlorhexidine) vs Another topical agent or placebo

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · HIV‐infected adults (> 13 years of age, per CDC) with one or more painful intraoral aphthous ulcers

The review found no eligible studies for this question.

1 finding from 1 review
  • No studies were included in this review. A total of 233 abstracts were retrieved; 25 were selected as potentially eligible but all were excluded (10 reported systemic rather than topical treatment; 3 non‐RCTs; 6…
    0 studies
    No studies found

Cognitive behavioural (group psychotherapy) therapy vs Placebo pill

Improvement in burning mouth symptoms · Adults over 18 years of age with chronic orofacial pain (burning mouth syndrome)

Cognitive behavioural (group psychotherapy) therapy showed no clear difference in improvement in burning mouth symptoms compared with placebo pill; GRADE not reported.

1 finding from 1 review

Antiseptic mouthwash (e.g. chlorhexidine) vs Another topical agent or placebo

Duration to heal oral ulcerations after initiation of treatment · HIV‐infected adults (> 13 years of age, per CDC) with one or more painful intraoral aphthous ulcers

The review found no eligible studies for this question.

1 finding from 1 review
  • No studies were included in this review. A total of 233 abstracts were retrieved; 25 were selected as potentially eligible but all were excluded (10 reported systemic rather than topical treatment; 3 non‐RCTs; 6…
    0 studies
    No studies found

Antiseptic mouthwash (e.g. chlorhexidine) vs Another topical agent or placebo

Healing of ulceration · HIV‐infected adults (> 13 years of age, per CDC) with one or more painful intraoral aphthous ulcers

The review found no eligible studies for this question.

1 finding from 1 review
  • No studies were included in this review. A total of 233 abstracts were retrieved; 25 were selected as potentially eligible but all were excluded (10 reported systemic rather than topical treatment; 3 non‐RCTs; 6…
    0 studies
    No studies found

Antiseptic mouthwash (e.g. chlorhexidine) vs Another topical agent or placebo

Incidence and recurrence after healing of ulcers · HIV‐infected adults (> 13 years of age, per CDC) with one or more painful intraoral aphthous ulcers

The review found no eligible studies for this question.

1 finding from 1 review
  • No studies were included in this review. A total of 233 abstracts were retrieved; 25 were selected as potentially eligible but all were excluded (10 reported systemic rather than topical treatment; 3 non‐RCTs; 6…
    0 studies
    No studies found

Antiseptic mouthwash (e.g. chlorhexidine) vs Another topical agent or placebo

Adverse effects of long‐term use of available topical agents · HIV‐infected adults (> 13 years of age, per CDC) with one or more painful intraoral aphthous ulcers

The review found no eligible studies for this question.

1 finding from 1 review
  • No studies were included in this review. A total of 233 abstracts were retrieved; 25 were selected as potentially eligible but all were excluded (10 reported systemic rather than topical treatment; 3 non‐RCTs; 6…
    0 studies
    No studies found