Findings

What do systematic reviews say?

4 questions · 4 findings · 1 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 4 · 100%Moderate 0 · 0%High 0 · 0%

Participants with at least some Side Effects · cannabis dependence

Mixed action antidepressant showed no clear difference in participants experiencing adverse effects compared with placebo (low certainty).

1 finding from 1 review

Pharmacotherapies for cannabis dependence 2019 · Cochrane Headline outcomes only
RR 0.93 [0.55, 1.55]
1 study · 76 participants
Low

Withdrawals due to adverse events · cannabis dependence

Mixed action antidepressant showed no clear difference in participants withdrawn due to adverse effects compared with placebo (low certainty).

1 finding from 1 review

Pharmacotherapies for cannabis dependence 2019 · Cochrane Headline outcomes only
RR 1.44 [0.11, 18.9]
2 studies · 179 participants
Low

Completion of scheduled treatment · cannabis dependence

Mixed action antidepressant showed no clear difference in completion of scheduled treatment compared with placebo (low certainty).

1 finding from 1 review

Pharmacotherapies for cannabis dependence 2019 · Cochrane Headline outcomes only
RR 0.93 [0.71, 1.21]
2 studies · 169 participants
Low

Abstinence · cannabis dependence

Mixed action antidepressant showed no clear difference in participants abstinent at end of treatment compared with placebo (low certainty).

1 finding from 1 review

Pharmacotherapies for cannabis dependence 2019 · Cochrane Headline outcomes only
RR 0.82 [0.12, 5.41]
2 studies · 179 participants
Low