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Evidence found and GRADE certainty

7 questions · 7 findings · 1 reviews · Schizophrenia

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No studies found 2 · 28.6%GRADE not reported 0 · 0%Very low 3 · 42.9%Low 1 · 14.3%Moderate 1 · 14.3%High 0 · 0%

Mirtazapine adjunct vs placebo adjunct

Mental state: 2a. Negative symptoms ‐ No clinical important improvement ‐ negative symptoms (SANS) · schizophrenia

It is very uncertain whether mirtazapine adjunct changes mental state: specific negative symptoms ‐ clinically important… compared with placebo adjunct (very low certainty).

1 finding from 1 review

Mirtazapine adjunct vs placebo adjunct

Mental state: clinically important change in mental state · schizophrenia

It is very uncertain whether mirtazapine adjunct changes mental state: overall mental state ‐ clinically important change* compared with placebo adjunct (very low certainty).

1 finding from 1 review

Mirtazapine adjunct vs placebo adjunct

Adverse effect/event: clinically important extrapyramidal adverse events ‐ akathisia (medium term) · schizophrenia

Mirtazapine adjunct may leads to lower adverse effects: extrapyramidal ‐ clinically important change… compared with placebo adjunct (low certainty).

1 finding from 1 review