Azathioprine vs methotrexate
Death · adults with renal vasculitis for maintenance therapy
Azathioprine may leads to lower death compared with methotrexate (low certainty).
1 finding from 1 review
- RR 0.331 study · 126 participantsLow
Findings
What do systematic reviews say?
12 questions · 12 findings · 1 reviews · Kidney and Transplant · Headline outcomes only
No studies found 5 · 41.7%GRADE not reported 0 · 0%Very low 0 · 0%Low 7 · 58.3%Moderate 0 · 0%High 0 · 0%
Azathioprine vs methotrexate
Kidney function · adults with renal vasculitis for maintenance therapy
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Azathioprine vs methotrexate
Dialysis · adults with renal vasculitis for maintenance therapy
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Azathioprine vs methotrexate
Relapse · adults with renal vasculitis for maintenance therapy
Azathioprine showed no clear difference in relapse compared with methotrexate (low certainty).
1 finding from 1 review
- RR 1.1 [0.68, 1.77]1 study · 126 participantsLow
Azathioprine vs methotrexate
Adverse event causing death or study drug discontinuation · adults with renal vasculitis for maintenance therapy
Azathioprine showed no clear difference in adverse events causing death or study drug discontinuation compared with methotrexate (low certainty).
1 finding from 1 review
- RR 0.58 [0.25, 1.38]1 study · 126 participantsLow
Azathioprine vs methotrexate
Severe adverse events · adults with renal vasculitis for maintenance therapy
Azathioprine may leads to lower severe adverse events compared with methotrexate (low certainty).
1 finding from 1 review
- RR 0.581 study · 126 participantsLow
Leflunomide vs methotrexate
Death · adults with renal vasculitis for maintenance therapy
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Leflunomide vs methotrexate
Kidney function · adults with renal vasculitis for maintenance therapy
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Leflunomide vs methotrexate
Dialysis · adults with renal vasculitis for maintenance therapy
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Leflunomide vs methotrexate
Relapse · adults with renal vasculitis for maintenance therapy
Leflunomide showed no clear difference in relapse compared with methotrexate (low certainty).
1 finding from 1 review
- RR 0.5 [0.22, 1.11]1 study · 54 participantsLow
Leflunomide vs methotrexate
Serious adverse events* · adults with renal vasculitis for maintenance therapy
Leflunomide showed no clear difference in serious adverse events* compared with methotrexate (low certainty).
1 finding from 1 review
- RR 11.81 [0.69, 203.68]1 study · 54 participantsLow
Leflunomide vs methotrexate
Infection · adults with renal vasculitis for maintenance therapy
Leflunomide showed no clear difference in infection compared with methotrexate (low certainty).
1 finding from 1 review
- RR 1.17 [0.27, 106.88]1 study · 54 participantsLow