Findings

What do systematic reviews say?

8 questions · 8 findings · 2 reviews · Gynaecology and Fertility

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No studies found 2 · 25%GRADE not reported 0 · 0%Very low 4 · 50%Low 2 · 25%Moderate 0 · 0%High 0 · 0%

Intervention not reported

Adverse events ‐ Ectopic pregnancy Melatonin lower dose versus melatonin higher dose№ of participants: 120(1 RCT) · women with subfertility

1 finding from 1 review

Antioxidants for female subfertility 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Intervention not reported

Live birth; type of antioxidant (natural conceptions and undergoing fertility treatments) ‐ Melatonin lower dose versus melatonin higher dose№ of participants: 140(2 RCTs) · women with subfertility

The intervention showed no clear difference in live birth; type of antioxidant (natural conceptions and undergoing… (low certainty).

1 finding from 1 review

Antioxidants for female subfertility 2020 · Cochrane Headline outcomes only
OR 0.94 [0.41, 2.15]
Studies not reported
Low

Intervention not reported

Clinical pregnancy; type of antioxidant (natural conceptions and undergoing fertility treatments) ‐ Melatonin lower dose versus melatonin higher dose№ of participants: 140(2 RCTs) · women with subfertility

The intervention showed no clear difference in clinical pregnancy; type of antioxidant (natural conceptions and… (low certainty).

1 finding from 1 review

Antioxidants for female subfertility 2020 · Cochrane Headline outcomes only
OR 0.94 [0.41, 2.15]
Studies not reported
Low

Myo‐inositol vs antioxidant (melatonin)

Ovulation · subfertile women with polycystic ovary syndrome

The review found no eligible studies for this question.

1 finding from 1 review

Inositol for subfertile women with polycystic ovary syndrome 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Myo‐inositol vs antioxidant (melatonin)

Live birth · subfertile women with polycystic ovary syndrome

The review found no eligible studies for this question.

1 finding from 1 review

Inositol for subfertile women with polycystic ovary syndrome 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Myo‐inositol vs antioxidant (melatonin)

Adverse events ‐ Miscarriage · subfertile women with polycystic ovary syndrome

It is very uncertain whether myo‐inositol changes adverse event ‐ miscarriage compared with antioxidant (melatonin) (very low certainty).

1 finding from 1 review

Inositol for subfertile women with polycystic ovary syndrome 2018 · Cochrane Headline outcomes only
OR 0.7 [0.22, 2.24]
1 study · 358 participants
Very low

Myo‐inositol vs antioxidant (melatonin)

Adverse event ‐ multiple pregnancy · subfertile women with polycystic ovary syndrome

It is very uncertain whether myo‐inositol changes adverse event ‐ multiple pregnancy compared with antioxidant (melatonin) (very low certainty).

1 finding from 1 review

Inositol for subfertile women with polycystic ovary syndrome 2018 · Cochrane Headline outcomes only
OR 0.95 [0.57, 1.59]
1 study · 358 participants
Very low

Myo‐inositol vs antioxidant (melatonin)

Clinical pregnancy · subfertile women with polycystic ovary syndrome

It is very uncertain whether myo‐inositol changes clinical pregnancy compared with antioxidant (melatonin) (very low certainty).

1 finding from 1 review

Inositol for subfertile women with polycystic ovary syndrome 2018 · Cochrane Headline outcomes only
OR 0.83 [0.53, 1.28]
1 study · 358 participants
Very low