Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

101 questions · 119 findings · 11 reviews · Gynaecology and Fertility · Headline outcomes only

No studies found 18 · 15.1%GRADE not reported 0 · 0%Very low 41 · 34.5%Low 36 · 30.3%Moderate 21 · 17.6%High 3 · 2.5%

Presurgical medical therapy vs postsurgical medical therapy

Pain recurrence (dichotomous) Pain recurrence ≤ 12 months · women having endometriosis surgery

Presurgical medical therapy showed no clear difference in pain recurrence (dichotomous) Pain recurrence ≤ 12 months compared with postsurgical medical therapy (low certainty).

1 finding from 1 review

Presurgical medical therapy vs Placebo or no active treatment

Pain recurrence (dichotomous) Pain recurrence ≤ 12 months · women having endometriosis surgery

It is very uncertain whether presurgical medical therapy changes pain recurrence (dichotomous) Pain recurrence ≤ 12 months compared with placebo or no medical therapy (very low certainty).

1 finding from 1 review

Presurgical medical therapy vs Placebo or no active treatment

Disease recurrence ≤ 12 months (EEC stage) · women having endometriosis surgery

It is very uncertain whether presurgical medical therapy changes disease recurrence ≤ 12 months (EEC stage) compared with placebo or no medical therapy (very low certainty).

1 finding from 1 review

Postsurgical medical therapy vs Placebo or no active treatment

Disease recurrence ≤ 12 months (EEC stage) · women having endometriosis surgery

It is very uncertain whether postsurgical medical therapy changes disease recurrence ≤ 12 months (EEC stage) compared with placebo or no medical therapy (very low certainty).

1 finding from 1 review

Postsurgical medical therapy vs Placebo or no active treatment

Pain recurrence (dichotomous) Pain recurrence ≤ 12 months · women having endometriosis surgery

Postsurgical medical therapy may leads to lower pain recurrence (dichotomous) Pain recurrence ≤ 12 months compared with placebo or no medical therapy (low certainty).

1 finding from 1 review

LOD with and without medical ovulation vs medical ovulation induction alone

Live birth · women with anovulatory PCOS and CC resistance

LOD with and without medical ovulation may leads to lower live birth compared with medical ovulation induction alone (low certainty).

2 findings from 1 review

LOD with and without medical ovulation vs medical ovulation induction alone

Multiple pregnancy · women with anovulatory PCOS and CC resistance

LOD with and without medical ovulation probably leads to lower multiple pregnancy compared with medical ovulation induction alone (moderate certainty).

1 finding from 1 review