Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

7 questions · 12 findings · 2 reviews · Dental caries · All outcomes

No studies found 0 · 0%GRADE not reported 9 · 75%Very low 0 · 0%Low 0 · 0%Moderate 3 · 25%High 0 · 0%

Bleaching before resin infiltration (bleaching + infiltration) vs Resin infiltration alone

Masking effect (esthetic improvement) · Patients with dental fluorosis

Bleaching before resin infiltration did not improve masking of fluorosis compared with infiltration alone (MD -0.30, 95% CI -0.98 to 0.39; moderate certainty).

1 finding from 1 review

Machine-learning algorithms for dental caries detection vs Different machine-learning algorithms compared with one another / against the reference caries diagnosis

Diagnostic accuracy for root caries detection · Dental radiographic/intraoral images of human teeth (X-ray and photographic)

One study reported machine-learning accuracy for root caries detection (97.1%, support vector machine); not pooled and not graded.

1 finding from 1 review

Resin infiltration vs Untreated control (natural remineralization)

Optical/esthetic improvement (visual-tactile assessment) · Patients with post-orthodontic white spot lesions (WSL)

Resin infiltration produced significantly greater optical improvement of white spot lesions than untreated (naturally remineralizing) controls (SMD 1.24, 95% CI 0.59 to 1.88; moderate certainty).

4 findings from 1 review
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Bleaching before resin infiltration (bleaching + infiltration) vs Resin infiltration alone

Patient/dentist satisfaction · Patients with dental fluorosis

Patient/dentist satisfaction did not differ between bleaching-then-infiltration and infiltration alone (SMD -1.53, 95% CI -4.75 to 1.70; ungraded).

1 finding from 1 review

Resin infiltration vs Fluoride varnish

Optical/esthetic improvement (DIAGNOdent reading) · Patients (mainly children) with white spot lesions (WSL)

Resin infiltration produced significantly greater optical improvement than fluoride varnish (MD 4.76, 95% CI 0.74 to 8.78; moderate certainty).

3 findings from 1 review