Findings

What do systematic reviews say?

6 questions · 6 findings · 2 reviews · Acute Respiratory Infections

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 6 · 100%Moderate 0 · 0%High 0 · 0%

Resolution of symptoms post‐treatment (ITT analysis) · group A streptococcal pharyngitis

Macrolides showed no clear difference in resolution of symptoms post‐treatment (ITT analysis) compared with penicillin (low certainty).

1 finding from 1 review

Different antibiotic treatments for group A streptococcal pharyngitis 2023 · Cochrane Headline outcomes only
OR 1.11 [0.92, 1.35]
6 studies · 1728 participants
Low

Resolution of symptoms post‐treatment (evaluable participants) · group A streptococcal pharyngitis

Macrolides showed no clear difference in resolution of symptoms post‐treatment (evaluable participants) compared with penicillin (low certainty).

1 finding from 1 review

Different antibiotic treatments for group A streptococcal pharyngitis 2023 · Cochrane Headline outcomes only
OR 0.79 [0.57, 1.09]
6 studies · 1159 participants
Low

Relapse · group A streptococcal pharyngitis

Macrolides showed no clear difference in incidence of relapse (evaluable participants) compared with penicillin (low certainty).

1 finding from 1 review

Different antibiotic treatments for group A streptococcal pharyngitis 2023 · Cochrane Headline outcomes only
OR 1.21 [0.48, 3.03]
6 studies · 802 participants
Low

Adverse events (ITT analysis) · group A streptococcal pharyngitis

Macrolides showed no clear difference in adverse events (ITT analysis) compared with penicillin (low certainty).

1 finding from 1 review

Different antibiotic treatments for group A streptococcal pharyngitis 2023 · Cochrane Headline outcomes only
OR 1.19 [0.82, 1.73]
6 studies · 1727 participants
Low

The rate of improvement in CT images ( · adults with diffuse panbronchiolitis

The intervention may leads to higher the rate of improvement in CT images ( (low certainty).

1 finding from 1 review

Macrolides for diffuse panbronchiolitis 2015 · Cochrane Headline outcomes only
RR 15.38 [1.05, 225.73]
1 study · 19 participants
Low

The rate of progress in CT images ( · adults with diffuse panbronchiolitis

The intervention may leads to lower the rate of progress in CT images ( (low certainty).

1 finding from 1 review

Macrolides for diffuse panbronchiolitis 2015 · Cochrane Headline outcomes only
RR 0.06 [0, 0.88]
1 study · 19 participants
Low