Findings

What do systematic reviews say?

21 questions · 21 findings · 1 reviews

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No studies found 10 · 47.6%GRADE not reported 4 · 19%Very low 0 · 0%Low 7 · 33.3%Moderate 0 · 0%High 0 · 0%

Low‐dose colchicine vs placebo

Pain ‐ not reported · acute gout

The review found no eligible studies for this question.

1 finding from 1 review

Colchicine for acute gout 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Low‐dose colchicine vs placebo

Participant global assessment of treatment success: proportion with 50% or greater decrease in pain score from baseline ‐ 32 to 36 hours · acute gout

Low‐dose colchicine may leads to higher participant global assessment of treatment success: proportion with… compared with placebo (low certainty).

1 finding from 1 review

Colchicine for acute gout 2021 · Cochrane Headline outcomes only
RR 2.43 [1.05, 5.64]
1 study · 103 participants
Low

Low‐dose colchicine vs NSAIDs

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · acute gout

1 finding from 1 review

Colchicine for acute gout 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 399 participants
Low

Low‐dose colchicine vs NSAIDs

Global assessment of treatment success · acute gout

Low‐dose colchicine showed no clear difference in participant global assessment of treatment success: Completely… compared with NSAIDs (low certainty).

1 finding from 1 review

Colchicine for acute gout 2021 · Cochrane Headline outcomes only
RR 0.97 [0.82, 1.15]
1 study · 399 participants
Low

Low‐dose colchicine vs NSAIDs

Reduction of inflammation ‐ not measured · acute gout

The review found no eligible studies for this question.

1 finding from 1 review

Colchicine for acute gout 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Low‐dose colchicine vs NSAIDs

Function of target joint ‐ not measured · acute gout

The review found no eligible studies for this question.

1 finding from 1 review

Colchicine for acute gout 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Low‐dose colchicine vs NSAIDs

Serious adverse events · acute gout

The review found no eligible studies for this question.

1 finding from 1 review

Colchicine for acute gout 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Low‐dose colchicine vs NSAIDs

Number of participants reporting an adverse event · acute gout

Low‐dose colchicine showed no clear difference in total number of participants reporting adverse events compared with NSAIDs (low certainty).

1 finding from 1 review

Colchicine for acute gout 2021 · Cochrane Headline outcomes only
RR 1.07 [0.88, 1.29]
1 study · 399 participants
Low

Low‐dose colchicine vs NSAIDs

Withdrawals due to adverse events · acute gout

The review found no eligible studies for this question.

1 finding from 1 review

Colchicine for acute gout 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Low‐dose colchicine vs placebo

Reduction of inflammation ‐ not measured · acute gout

The review found no eligible studies for this question.

1 finding from 1 review

Colchicine for acute gout 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Low‐dose colchicine vs placebo

Function of target joint ‐ not measured · acute gout

The review found no eligible studies for this question.

1 finding from 1 review

Colchicine for acute gout 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Low‐dose colchicine vs placebo

Serious adverse events · acute gout

1 finding from 1 review

Colchicine for acute gout 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 133 participants
GRADE not reported

Low‐dose colchicine vs placebo

Total adverse events · acute gout

Low‐dose colchicine showed no clear difference in total adverse events compared with placebo (low certainty).

1 finding from 1 review

Colchicine for acute gout 2021 · Cochrane Headline outcomes only
RR 1.32 [0.68, 2.56]
1 study · 103 participants
Low

Low‐dose colchicine vs placebo

Withdrawals due to adverse events · acute gout

1 finding from 1 review

Colchicine for acute gout 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 133 participants
GRADE not reported

High‐dose vs low‐dose colchicine

Pain ‐ not reported · acute gout

The review found no eligible studies for this question.

1 finding from 1 review

Colchicine for acute gout 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

High‐dose vs low‐dose colchicine

Participant global assessment of treatment success: proportion with 50% or greater decrease in pain score from baseline ‐ 32 to 36 hours · acute gout

High‐dose showed no clear difference in participant global assessment of treatment success: proportion with… compared with low‐dose colchicine (low certainty).

1 finding from 1 review

Colchicine for acute gout 2021 · Cochrane Headline outcomes only
RR 0.87 [0.56, 1.36]
1 study · 126 participants
Low

High‐dose vs low‐dose colchicine

Reduction of inflammation ‐ not measured · acute gout

The review found no eligible studies for this question.

1 finding from 1 review

Colchicine for acute gout 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

High‐dose vs low‐dose colchicine

Function of target joint ‐ not measured · acute gout

The review found no eligible studies for this question.

1 finding from 1 review

Colchicine for acute gout 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

High‐dose vs low‐dose colchicine

Serious adverse events · acute gout

1 finding from 1 review

Colchicine for acute gout 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 126 participants
GRADE not reported

High‐dose vs low‐dose colchicine

Total adverse events · acute gout

High‐dose may leads to higher total adverse events compared with low‐dose colchicine (low certainty).

1 finding from 1 review

Colchicine for acute gout 2021 · Cochrane Headline outcomes only
RR 2.11 [1.51, 2.95]
1 study · 126 participants
Low