Findings

What do systematic reviews say?

4 questions · 6 findings · 1 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 2 · 33.3%Low 1 · 16.7%Moderate 3 · 50%High 0 · 0%

Live birth rate

Long‐acting FSH (all doses) probably leads to lower live birth rate ‐ Low dose (60 to 120 μg) compared with daily FSH (moderate certainty).

3 findings from 1 review

Long‐acting FSH versus daily FSH for women undergoing assisted reproduction 2015 · Cochrane Headline outcomes only
RR 0.7 [0.52, 0.93]
3 studies · 645 participants
Moderate
Long‐acting FSH versus daily FSH for women undergoing assisted reproduction 2015 · Cochrane Headline outcomes only
RR 1.03 [0.9, 1.18]
4 studies · 1685 participants
Moderate
Long‐acting FSH versus daily FSH for women undergoing assisted reproduction 2015 · Cochrane Headline outcomes only
RR 0.43 [0.12, 1.52]
1 study · 33 participants
Very low

OHSS ‐ Low dose (60 to 120 μg)

Long‐acting FSH (all doses) showed no clear difference in OHSS ‐ Low dose (60 to 120 μg) compared with daily FSH (moderate certainty).

1 finding from 1 review

Long‐acting FSH versus daily FSH for women undergoing assisted reproduction 2015 · Cochrane Headline outcomes only
RR 1.22 [0.56, 2.66]
3 studies · 645 participants
Moderate

OHSS ‐ Medium dose (150 to 180 μg)

Long‐acting FSH (all doses) showed no clear difference in OHSS ‐ Medium dose (150 to 180 μg) compared with daily FSH (low certainty).

1 finding from 1 review

Long‐acting FSH versus daily FSH for women undergoing assisted reproduction 2015 · Cochrane Headline outcomes only
RR 0.96 [0.68, 1.35]
5 studies · 3075 participants
Low

OHSS ‐ High dose (240 μg)

It is very uncertain whether long‐acting FSH (all doses) changes OHSS ‐ High dose (240 μg) compared with daily FSH (very low certainty).

1 finding from 1 review

Long‐acting FSH versus daily FSH for women undergoing assisted reproduction 2015 · Cochrane Headline outcomes only
RR 1.73 [0.09, 32.75]
1 study · 33 participants
Very low