What do systematic reviews say?

LOD of one ovary (unilateral) vs LOD of both ovaries (bilateral)

It is very uncertain whether LOD of one ovary (unilateral) changes miscarriage compared with LOD of both ovaries (bilateral) (very low certainty).

• Laparoscopic ovarian drilling for ovulation induction in women with anovulatory polycystic ovary syndrome 2020 · Cochrane Headline outcomes only
  Peto OR 1.02 [0.31, 3.33]
  2 studies · 131 participants
  Very low

LOD of one ovary (unilateral) vs LOD of both ovaries (bilateral)

The review found no eligible studies for this question.

• Laparoscopic ovarian drilling for ovulation induction in women with anovulatory polycystic ovary syndrome 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

LOD of one ovary (unilateral) vs LOD of both ovaries (bilateral)

It is very uncertain whether LOD of one ovary (unilateral) changes live birth compared with LOD of both ovaries (bilateral) (very low certainty).

• Laparoscopic ovarian drilling for ovulation induction in women with anovulatory polycystic ovary syndrome 2020 · Cochrane Headline outcomes only
  OR 0.83 [0.24, 2.78]
  1 study · 44 participants
  Very low

LOD of one ovary (unilateral) vs LOD of both ovaries (bilateral)

The review found no eligible studies for this question.

• Laparoscopic ovarian drilling for ovulation induction in women with anovulatory polycystic ovary syndrome 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

LOD of one ovary (unilateral) vs LOD of both ovaries (bilateral)

LOD of one ovary (unilateral) may leads to lower clinical pregnancy compared with LOD of both ovaries (bilateral) (low certainty).

• Laparoscopic ovarian drilling for ovulation induction in women with anovulatory polycystic ovary syndrome 2020 · Cochrane Headline outcomes only
  OR 0.57 [0.39, 0.84]
  7 studies · 470 participants
  Low

Effect of GnRHas vs other hormonal treatment on bone mineral density

• Gonadotropin‐releasing hormone analogues for endometriosis 2023 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 43 participants
  Very low

LOD vs other surgical interventions

LOD showed no clear difference in menstrual regularity ‐ LOD vs unilateral LOD N of participants: 104… compared with other surgical interventions (moderate certainty).

• Ovarian surgery for symptom relief in women with polycystic ovary syndrome 2017 · Cochrane Headline outcomes only
  OR 1.51 [0.62, 3.71]
  Studies not reported
  Moderate

Starting administration of the progestogen earlier vs starting administration of the progestogen later

The review found no eligible studies for this question.

• Endometrial preparation for women undergoing embryo transfer with frozen embryos or embryos derived from donor oocytes 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Starting administration of the progestogen earlier vs starting administration of the progestogen later

Starting administration of the progestogen earlier probably leads to higher clinical pregnancy rate compared with starting administration of the progestogen later (moderate certainty).

• Endometrial preparation for women undergoing embryo transfer with frozen embryos or embryos derived from donor oocytes 2020 · Cochrane Headline outcomes only
  OR 1.87 [1.13, 3.08]
  1 study · 282 participants
  Moderate

Starting administration of the progestogen earlier vs starting administration of the progestogen later

It is very uncertain whether starting administration of the progestogen earlier changes miscarriage Rate compared with starting administration of the progestogen later (very low certainty).

• Endometrial preparation for women undergoing embryo transfer with frozen embryos or embryos derived from donor oocytes 2020 · Cochrane Headline outcomes only
  OR 0.45 [0.16, 1.25]
  1 study · 191 participants
  Very low

Starting administration of the progestogen earlier vs starting administration of the progestogen later

• Endometrial preparation for women undergoing embryo transfer with frozen embryos or embryos derived from donor oocytes 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 282 participants
  Very low

Starting administration of the progestogen earlier vs starting administration of the progestogen later

Starting administration of the progestogen earlier probably leads to lower cycle cancellation rate compared with starting administration of the progestogen later (moderate certainty).

• Endometrial preparation for women undergoing embryo transfer with frozen embryos or embryos derived from donor oocytes 2020 · Cochrane Headline outcomes only
  OR 0.28 [0.11, 0.74]
  1 study · 282 participants
  Moderate

Starting administration of the progestogen earlier vs starting administration of the progestogen later

The review found no eligible studies for this question.

• Endometrial preparation for women undergoing embryo transfer with frozen embryos or embryos derived from donor oocytes 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Starting administration of the progestogen earlier vs starting administration of the progestogen later

The review found no eligible studies for this question.

• Endometrial preparation for women undergoing embryo transfer with frozen embryos or embryos derived from donor oocytes 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Coasting vs early unilateral follicular aspiration

The review found no eligible studies for this question.

• Coasting (withholding gonadotrophins) for preventing ovarian hyperstimulation syndrome 2017 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Coasting vs early unilateral follicular aspiration

It is very uncertain whether coasting changes OHSS compared with early unilateral follicular aspiration (very low certainty).

• Coasting (withholding gonadotrophins) for preventing ovarian hyperstimulation syndrome 2017 · Cochrane Headline outcomes only
  OR 0.98 [0.34, 2.85]
  2 studies · 83 participants
  Very low

Coasting vs early unilateral follicular aspiration

The review found no eligible studies for this question.

• Coasting (withholding gonadotrophins) for preventing ovarian hyperstimulation syndrome 2017 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Coasting vs early unilateral follicular aspiration

It is very uncertain whether coasting changes clinical Pregnancy compared with early unilateral follicular aspiration (very low certainty).

• Coasting (withholding gonadotrophins) for preventing ovarian hyperstimulation syndrome 2017 · Cochrane Headline outcomes only
  OR 0.67 [0.25, 1.79]
  2 studies · 83 participants
  Very low

Coasting vs early unilateral follicular aspiration

The review found no eligible studies for this question.

• Coasting (withholding gonadotrophins) for preventing ovarian hyperstimulation syndrome 2017 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found