Findings

What do systematic reviews say?

6 questions · 6 findings · 1 reviews

Sort:Best matchNewest Highest certainty Download CSV

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 16.7%Moderate 5 · 83.3%High 0 · 0%

Intravitreal fluocinolone acetonide implant 0.19 mg vs sham

Change in visual acuity (logMAR) ‐ 12 months (negative is better) · macular edema in diabetes

1 finding from 1 review

Intravitreal steroids for macular edema in diabetes 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 560 participants
Moderate

Intravitreal fluocinolone acetonide implant 0.19 mg vs sham

Gain 3+ lines of visual acuity at 1 year · macular edema in diabetes

Intravitreal fluocinolone acetonide implant 0.19 mg probably leads to higher gain of three or more lines visual acuity ‐ 12 months compared with sham (moderate certainty).

1 finding from 1 review

Intravitreal steroids for macular edema in diabetes 2020 · Cochrane Headline outcomes only
RR 1.79 [1.16, 2.78]
1 study · 560 participants
Moderate

Intravitreal fluocinolone acetonide implant 0.19 mg vs sham

Change in retinal thickness (micron) ‐ 12 months (negative is better) · macular edema in diabetes

1 finding from 1 review

Intravitreal steroids for macular edema in diabetes 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 560 participants
Moderate

Intravitreal fluocinolone acetonide implant 0.19 mg vs sham

Cataract progression ‐ 24 months · macular edema in diabetes

Intravitreal fluocinolone acetonide implant 0.19 mg probably leads to higher cataract progression ‐ 24 months compared with sham (moderate certainty).

1 finding from 1 review

Intravitreal steroids for macular edema in diabetes 2020 · Cochrane Headline outcomes only
RR 1.63 [1.35, 1.97]
1 study · 355 participants
Moderate

Intravitreal fluocinolone acetonide implant 0.19 mg vs sham

Use of IOP‐lowering medications ‐ 24 months · macular edema in diabetes

Intravitreal fluocinolone acetonide implant 0.19 mg probably leads to higher use of IOP‐lowering medications ‐ 24 months compared with sham (moderate certainty).

1 finding from 1 review

Intravitreal steroids for macular edema in diabetes 2020 · Cochrane Headline outcomes only
RR 2.72 [1.87, 3.98]
1 study · 558 participants
Moderate

Intravitreal fluocinolone acetonide implant 0.19 mg vs sham

Surgery for glaucoma ‐ 24 months · macular edema in diabetes

Intravitreal fluocinolone acetonide implant 0.19 mg may leads to higher surgery for glaucoma ‐ 24 months compared with sham (low certainty).

1 finding from 1 review

Intravitreal steroids for macular edema in diabetes 2020 · Cochrane Headline outcomes only
RR 9.54 [1.28, 70.93]
1 study · 558 participants
Low