Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

10 questions · 10 findings · 2 reviews

No studies found 4 · 40%GRADE not reported 0 · 0%Very low 1 · 10%Low 5 · 50%Moderate 0 · 0%High 0 · 0%

Interferon + chemotherapy vs chemotherapy alone

Adverse event (flu‐like symptoms) · Women with advanced (Stage II‐IV) epithelial ovarian cancer who have undergone surgery

Interferon + chemotherapy showed no clear difference in adverse event (flu‐like symptoms) compared with chemotherapy alone (low certainty).

1 finding from 1 review

Neoadjuvant immunotherapy (high dose interferon) plus chemotherapy vs neoadjuvant chemotherapy

Overall response rate (ORR), · stage III and IV cutaneous melanoma

It is very uncertain whether neoadjuvant immunotherapy (high dose interferon) plus chemotherapy changes overall response rate (ORR), measured after 8 weeks of treatment and… compared with neoadjuvant chemotherapy (very low certainty).

1 finding from 1 review