What do systematic reviews say?

Intentional endometrial injury vs no intervention or a sham procedure

Intentional endometrial injury showed no clear difference in live birth (primary analysis) compared with no intervention or a sham procedure (low certainty).

• Endometrial injury for pregnancy following sexual intercourse or intrauterine insemination 2022 · Cochrane Headline outcomes only
  RR 1.11 [0.78, 1.59]
  1 study · 210 participants
  Low

Intentional endometrial injury vs no intervention or a sham procedure

It is very uncertain whether intentional endometrial injury changes live birth or ongoing pregnancy (sensitivity analysis) compared with no intervention or a sham procedure (very low certainty).

• Endometrial injury for pregnancy following sexual intercourse or intrauterine insemination 2022 · Cochrane Headline outcomes only
  RR 1.71 [1.32, 2.21]
  8 studies · 1522 participants
  Very low

Intentional endometrial injury vs no intervention or a sham procedure

• Endometrial injury for pregnancy following sexual intercourse or intrauterine insemination 2022 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  Low
• Endometrial injury for pregnancy following sexual intercourse or intrauterine insemination 2022 · Cochrane Headline outcomes only
  RR 2.02 [1.67, 2.45]
  19 studies · 3184 participants
  Low

Intentional endometrial injury vs no intervention or a sham procedure

• Endometrial injury for pregnancy following sexual intercourse or intrauterine insemination 2022 · Cochrane Headline outcomes only
  no estimate extracted
  6 studies · 991 participants
  Very low