What do systematic reviews say?

More intensive vs less intensive insulin therapy

It is very uncertain whether more intensive changes transplant or graft survival compared with less intensive insulin therapy (very low certainty).

• Glucose‐lowering agents for treating pre‐existing and new‐onset diabetes in kidney transplant recipients 2020 · Cochrane Headline outcomes only
  RR 1.12 [0.32, 3.94]
  4 studies · 301 participants
  Very low

More intensive vs less intensive insulin therapy

It is very uncertain whether more intensive changes delayed graft function Time frame: 1 to 3 years compared with less intensive insulin therapy (very low certainty).

• Glucose‐lowering agents for treating pre‐existing and new‐onset diabetes in kidney transplant recipients 2020 · Cochrane Headline outcomes only
  RR 0.63 [0.42, 0.93]
  2 studies · 153 participants
  Very low

More intensive vs less intensive insulin therapy

• Glucose‐lowering agents for treating pre‐existing and new‐onset diabetes in kidney transplant recipients 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 16 participants
  Very low

More intensive vs less intensive insulin therapy

• Glucose‐lowering agents for treating pre‐existing and new‐onset diabetes in kidney transplant recipients 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 24 participants
  Very low

More intensive vs less intensive insulin therapy

• Glucose‐lowering agents for treating pre‐existing and new‐onset diabetes in kidney transplant recipients 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 36 participants
  Very low

More intensive vs less intensive insulin therapy

It is very uncertain whether more intensive changes death (any cause) Time frame: 1 to 5 years compared with less intensive insulin therapy (very low certainty).

• Glucose‐lowering agents for treating pre‐existing and new‐onset diabetes in kidney transplant recipients 2020 · Cochrane Headline outcomes only
  RR 0.68 [0.29, 1.58]
  3 studies · 208 participants
  Very low

More intensive vs less intensive insulin therapy

• Glucose‐lowering agents for treating pre‐existing and new‐onset diabetes in kidney transplant recipients 2020 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 301 participants
  Very low

More intensive vs less intensive insulin therapy

• Glucose‐lowering agents for treating pre‐existing and new‐onset diabetes in kidney transplant recipients 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 60 participants
  Very low