Maximal mouth opening (interincisal distance) · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF)
It is very uncertain whether intralesional dexamethasone injections changes maximal mouth opening (interincisal distance) compared with placebo injections (very low certainty).
2 findings from 1 review
Burning sensation (VAS 0-100) · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF)
It is very uncertain whether intralesional dexamethasone injections changes burning sensation (VAS 0-100) compared with placebo injections (very low certainty).
2 findings from 1 review
MD -52.00 [-62.04, -41.96]
1 study · 25 participants
Very low
MD -46.00 [-53.44, -38.56]
1 study · 25 participants
Very low
Adverse effects · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF)
1 finding from 1 review
Complications (adverse effects) · Adults (>18 years) with temporomandibular joint osteoarthritis (TMJ OA) diagnosed by RDC/TMD or compatible criteria
Intra-articular injection of sodium hyaluronate showed no clear difference in complications (adverse effects) compared with intra-articular injection of corticosteroids (betamethasone); GRADE not reported.
1 finding from 1 review
Presence of TMJ sounds · Adults (>18 years) with temporomandibular joint osteoarthritis (TMJ OA) diagnosed by RDC/TMD or compatible criteria
Intra-articular injection of sodium hyaluronate led to lower presence of TMJ sounds compared with intra-articular injection of corticosteroids (betamethasone); GRADE not reported.
1 finding from 1 review
Pain on palpation of the affected/contralateral TMJ and masticatory muscles · Adults (>18 years) with temporomandibular joint osteoarthritis (TMJ OA) diagnosed by RDC/TMD or compatible criteria
Intra-articular injection of sodium hyaluronate led to lower pain on palpation of the affected/contralateral TMJ and masticatory… compared with intra-articular injection of corticosteroids (betamethasone); GRADE not reported.
1 finding from 1 review
Pain on palpation of the affected and contralateral TMJ and masticatory muscles presented similar frequencies regardless of the time (Analyses 1.4-1.12); no statistically significant differences reported. Point…
1 study · 40 participants
GRADE not reported
Extent of mandibular movement (maximum jaw opening, lateral and contralateral movement, jaw protrusion) · Adults (>18 years) with temporomandibular joint osteoarthritis (TMJ OA) diagnosed by RDC/TMD or compatible criteria
Intra-articular injection of sodium hyaluronate showed no clear difference in extent of mandibular movement (maximum jaw opening, lateral and… compared with intra-articular injection of corticosteroids (betamethasone); GRADE not reported.
1 finding from 1 review
None of the mean differences between interventions for the measures of jaw movements (maximum jaw opening, lateral movement to affected side, contralateral movement, jaw protrusion; Analyses 1.16-1.27) showed…
1 study · 40 participants
GRADE not reported
Reported pain (mm on VAS) · Adults (>18 years) with temporomandibular joint osteoarthritis (TMJ OA) diagnosed by RDC/TMD or compatible criteria
Intra-articular injection of sodium hyaluronate led to lower reported pain (mm on VAS) compared with intra-articular injection of corticosteroids (betamethasone); GRADE not reported.
1 finding from 1 review
Maximal mouth opening (interincisal distance) · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF)
Intralesional steroid injection plus adjunctive treatment showed no clear difference in maximal mouth opening (interincisal distance) compared with intralesional steroid injection alone (low certainty).
2 findings from 1 review
Maximal mouth opening (interincisal distance) · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF)
Intralesional steroid injections showed no clear difference in maximal mouth opening (interincisal distance) compared with alternative medicinal treatments (low certainty).
2 findings from 1 review
Burning sensation (VAS 0-100) · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF)
It is very uncertain whether intralesional steroid injections changes burning sensation (VAS 0-100) compared with alternative medicinal treatments (very low certainty).
2 findings from 1 review
Completion of dental treatment · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia
The review found no eligible studies for this question.
1 finding from 1 review
Intraoperative pain · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia
1 finding from 1 review
pain (SEM scale); risk with conventional treatment -, risk with pre-cooling -; 160 (1 RCT); VERY LOW. Evidence is uncertain regarding the effect of pre-cooling of the injection site on pain (data presented in a form…
1 study · 160 participants
Very low
Adverse effects · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia
The review found no eligible studies for this question.
1 finding from 1 review
Acceptance of LA · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia
The review found no eligible studies for this question.
1 finding from 1 review
Patient satisfaction: measured by questionnaires · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia
The review found no eligible studies for this question.
1 finding from 1 review
Successful LA/painless treatment · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia
The review found no eligible studies for this question.
1 finding from 1 review
Lip or cheek biting · Children and young people aged 17 years or younger having dental treatment (including extractions) under general anaesthesia (secondary…
1 finding from 1 review
Coulthard 2006: lip/cheek biting 3/70 (LA) vs 1/69 (placebo), P=0.62; Townsend 2009: 4/11 vs 1/12, P=0.16; no statistically significant difference
2 studies · 162 participants
GRADE not reported
Parental satisfaction · Children and young people aged 17 years or younger having dental treatment (including extractions) under general anaesthesia (secondary…
The review found no eligible studies for this question.
1 finding from 1 review
Participant satisfaction · Children and young people aged 17 years or younger having dental treatment (including extractions) under general anaesthesia (secondary…
The review found no eligible studies for this question.
1 finding from 1 review