Findings

What do systematic reviews say?

7 questions · 7 findings · 1 reviews · Kidney and Transplant

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No studies found 1 · 14.3%GRADE not reported 0 · 0%Very low 0 · 0%Low 5 · 71.4%Moderate 1 · 14.3%High 0 · 0%

Macroplastique vs dextranomer/hyaluronic acid polymer (Deflux) to correct vesicoureteric reflux

Febrile UTI by 1 year · primary VUR

Macroplastique showed no clear difference in number of children with febrile UTI compared with dextranomer/hyaluronic acid polymer (Deflux) to correct… (low certainty).

1 finding from 1 review

Interventions for primary vesicoureteric reflux 2019 · Cochrane Headline outcomes only
RR 1.09 [0.45, 2.66]
1 study · 255 participants
Low

Macroplastique vs dextranomer/hyaluronic acid polymer (Deflux) to correct vesicoureteric reflux

Number of children with afebrile UTI · primary VUR

Macroplastique showed no clear difference in number of children with afebrile UTI compared with dextranomer/hyaluronic acid polymer (Deflux) to correct… (low certainty).

1 finding from 1 review

Interventions for primary vesicoureteric reflux 2019 · Cochrane Headline outcomes only
RR 1.68 [0.52, 5.44]
1 study · 72 participants
Low

Macroplastique vs dextranomer/hyaluronic acid polymer (Deflux) to correct vesicoureteric reflux

Number of ureters with persistent VUR > grade 1 at 1 year · primary VUR

Macroplastique probably leads to lower number of ureters with persistent VUR > grade 1 at 1 year compared with dextranomer/hyaluronic acid polymer (Deflux) to correct… (moderate certainty).

1 finding from 1 review

Interventions for primary vesicoureteric reflux 2019 · Cochrane Headline outcomes only
RR 0.54 [0.35, 0.83]
2 studies · 472 participants
Moderate

Macroplastique vs dextranomer/hyaluronic acid polymer (Deflux) to correct vesicoureteric reflux

Number of kidneys with temporary renal dilatation after injection · primary VUR

Macroplastique may leads to higher number of kidneys with temporary renal dilatation after injection compared with dextranomer/hyaluronic acid polymer (Deflux) to correct… (low certainty).

1 finding from 1 review

Interventions for primary vesicoureteric reflux 2019 · Cochrane Headline outcomes only
RR 1.85 [1.02, 3.35]
1 study · 114 participants
Low

Macroplastique vs dextranomer/hyaluronic acid polymer (Deflux) to correct vesicoureteric reflux

Ureteral obstruction · primary VUR

Macroplastique showed no clear difference in ureteral obstruction compared with dextranomer/hyaluronic acid polymer (Deflux) to correct… (low certainty).

1 finding from 1 review

Interventions for primary vesicoureteric reflux 2019 · Cochrane Headline outcomes only
RR 1.46 [0.25, 8.66]
1 study · 399 participants
Low

Macroplastique vs dextranomer/hyaluronic acid polymer (Deflux) to correct vesicoureteric reflux

Post operative flank pain · primary VUR

Macroplastique showed no clear difference in post operative flank pain compared with dextranomer/hyaluronic acid polymer (Deflux) to correct… (low certainty).

1 finding from 1 review

Interventions for primary vesicoureteric reflux 2019 · Cochrane Headline outcomes only
RR 1.45 [0.33, 6.36]
1 study · 255 participants
Low

Macroplastique vs dextranomer/hyaluronic acid polymer (Deflux) to correct vesicoureteric reflux

New renal parenchymal defects on DMSA scan (kidney injury) · primary VUR

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for primary vesicoureteric reflux 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found