Findings

What do systematic reviews say?

6 questions · 6 findings · 2 reviews · Oral and maxillofacial surgery

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 6 · 100%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

High-volume irrigation (~175 mL) vs Low-volume irrigation (~25 mL)

Wound infection · Adults with mandibular third molars requiring removal

It is very uncertain whether high-volume irrigation (~175 mL) changes wound infection compared with low-volume irrigation (~25 mL) (very low certainty).

1 finding from 1 review

Surgical techniques for the removal of mandibular wisdom teeth 2020 · Cochrane All outcomes
1 week · high vs low volume
RR 0.17 [0.02, 1.37]
1 study · 211 participants
Very low

High-volume irrigation (~175 mL) vs Low-volume irrigation (~25 mL)

Presence of dry socket · Adults with mandibular third molars requiring removal

It is very uncertain whether high-volume irrigation (~175 mL) changes alveolar osteitis compared with low-volume irrigation (~25 mL) (very low certainty).

1 finding from 1 review

Surgical techniques for the removal of mandibular wisdom teeth 2020 · Cochrane All outcomes
1 week · high vs low volume
RR 0.52 [0.27, 1.02]
1 study · 211 participants
Very low

Mechanical (high-volume) irrigation vs Manual (low-volume) irrigation

Wound infection · Adults with mandibular third molars requiring removal

It is very uncertain whether mechanical (high-volume) irrigation changes wound infection compared with manual (low-volume) irrigation (very low certainty).

1 finding from 1 review

Surgical techniques for the removal of mandibular wisdom teeth 2020 · Cochrane All outcomes
1 week · mechanical vs manual
RR 0.50 [0.05, 5.43]
1 study · 99 participants
Very low

Mechanical (high-volume) irrigation vs Manual (low-volume) irrigation

Presence of dry socket · Adults with mandibular third molars requiring removal

It is very uncertain whether mechanical (high-volume) irrigation changes alveolar osteitis compared with manual (low-volume) irrigation (very low certainty).

1 finding from 1 review

Surgical techniques for the removal of mandibular wisdom teeth 2020 · Cochrane All outcomes
1 week · mechanical vs manual
RR 0.33 [0.01, 8.09]
1 study · 99 participants
Very low

Fluoride gel (topically applied; operator- or self-applied; any fluoride agent/concentration; frequency at least once a year) vs High-content fluoride toothpaste (1350 ppm)

Adverse effects · Adults with head and neck cancer undergoing curative or adjuvant radiotherapy (at risk of osteoradionecrosis of the jaws)

1 finding from 1 review

Interventions for preventing osteoradionecrosis of the jaws in adults receiving head and neck radiotherapy 2019 · Cochrane All outcomes
14 to 36 months
Adverse effects were an outcome of interest in the study conducting this comparison, however no mention was made of the presence or absence of any adverse events
1 study · 220 participants
Very low

Fluoride gel (topically applied; operator- or self-applied; any fluoride agent/concentration; frequency at least once a year) vs High-content fluoride toothpaste (1350 ppm)

Incidence of ORN · Adults with head and neck cancer undergoing curative or adjuvant radiotherapy (at risk of osteoradionecrosis of the jaws)

1 finding from 1 review

Interventions for preventing osteoradionecrosis of the jaws in adults receiving head and neck radiotherapy 2019 · Cochrane All outcomes
14 to 36 months
This comparison was only made in 1 study, which showed no difference between the 2 interventions: no patients in either group developed ORN (12- to 36-month follow-up) (0/99 in the fluoride gel group and 0/91 in the…
1 study · 220 participants
Very low