Findings

What do systematic reviews say?

14 questions · 23 findings · 2 reviews · Developmental, Psychosocial and Learning Problems

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No studies found 1 · 4.3%GRADE not reported 9 · 39.1%Very low 5 · 21.7%Low 8 · 34.8%Moderate 0 · 0%High 0 · 0%

High‐dose methylphenidate vs placebo

Inattention Measured using SNAP‐IV inattention subscale (range 0 to 27) · Children aged 6 to 18 years with ASD

2 findings from 1 review

Methylphenidate for children and adolescents with autism spectrum disorder 2017 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 51 participants
Low
Methylphenidate for children and adolescents with autism spectrum disorder 2017 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 71 participants
Low

High‐dose methylphenidate vs placebo

Impulsivity · Children aged 6 to 18 years with ASD

2 findings from 1 review

Methylphenidate for children and adolescents with autism spectrum disorder 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 48 participants
GRADE not reported
Methylphenidate for children and adolescents with autism spectrum disorder 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 36 participants
GRADE not reported

High‐dose methylphenidate vs placebo

Hyperactivity · Children aged 6 to 18 years with ASD

2 findings from 1 review

Methylphenidate for children and adolescents with autism spectrum disorder 2017 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 71 participants
Low
Methylphenidate for children and adolescents with autism spectrum disorder 2017 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 73 participants
Low

High‐dose methylphenidate vs placebo

Impaired social interaction · Children aged 6 to 18 years with ASD

2 findings from 1 review

Methylphenidate for children and adolescents with autism spectrum disorder 2017 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 71 participants
Very low
Methylphenidate for children and adolescents with autism spectrum disorder 2017 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 63 participants
Very low

High‐dose methylphenidate vs placebo

Impaired communication · Children aged 6 to 18 years with ASD

2 findings from 1 review

Methylphenidate for children and adolescents with autism spectrum disorder 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 48 participants
GRADE not reported
Methylphenidate for children and adolescents with autism spectrum disorder 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 24 participants
GRADE not reported

High‐dose methylphenidate vs placebo

Stereotypical behaviours · Children aged 6 to 18 years with ASD

2 findings from 1 review

Methylphenidate for children and adolescents with autism spectrum disorder 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 48 participants
GRADE not reported
Methylphenidate for children and adolescents with autism spectrum disorder 2017 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 69 participants
Low

High‐dose methylphenidate vs placebo

Overall ASD · Children aged 6 to 18 years with ASD

2 findings from 1 review

Methylphenidate for children and adolescents with autism spectrum disorder 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 48 participants
GRADE not reported
Methylphenidate for children and adolescents with autism spectrum disorder 2017 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 36 participants
Low

High‐dose methylphenidate vs placebo

Total number of adverse events · Children aged 6 to 18 years with ASD

2 findings from 1 review

Methylphenidate for children and adolescents with autism spectrum disorder 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 108 participants
GRADE not reported
Methylphenidate for children and adolescents with autism spectrum disorder 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 79 participants
GRADE not reported

Constraint induced movement therapy (CIMT) vs high‐dose comparison

Unimanual capacity · children with unilateral cerebral palsy

2 findings from 1 review

Constraint‐induced movement therapy in children with unilateral cerebral palsy 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 34 participants
Very low
Constraint‐induced movement therapy in children with unilateral cerebral palsy 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 43 participants
Very low

Constraint induced movement therapy (CIMT) vs high‐dose comparison

Manual ability ‐ not measured · children with unilateral cerebral palsy

The review found no eligible studies for this question.

1 finding from 1 review

Constraint‐induced movement therapy in children with unilateral cerebral palsy 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Constraint induced movement therapy (CIMT) vs high‐dose comparison

Self‐care · children with unilateral cerebral palsy

1 finding from 1 review

Constraint‐induced movement therapy in children with unilateral cerebral palsy 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 34 participants
Very low

Constraint induced movement therapy (CIMT) vs high‐dose comparison

Individualised measures of performance · children with unilateral cerebral palsy

1 finding from 1 review

Constraint‐induced movement therapy in children with unilateral cerebral palsy 2019 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 126 participants
Low

Constraint induced movement therapy (CIMT) vs high‐dose comparison

Adverse events · children with unilateral cerebral palsy

1 finding from 1 review

Constraint‐induced movement therapy in children with unilateral cerebral palsy 2019 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 186 participants
GRADE not reported

Constraint induced movement therapy (CIMT) vs high‐dose comparison

Bimanual performance · children with unilateral cerebral palsy

1 finding from 1 review

Constraint‐induced movement therapy in children with unilateral cerebral palsy 2019 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 126 participants
Low