Findings

What do systematic reviews say?

8 questions · 8 findings · 1 reviews

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No studies found 4 · 50%GRADE not reported 0 · 0%Very low 2 · 25%Low 2 · 25%Moderate 0 · 0%High 0 · 0%

Heterologous vaccination scheme vs homologous vaccination scheme

Confirmed SARS‐CoV‐2 infection

The review found no eligible studies for this question.

1 finding from 1 review

Efficacy and safety of COVID‐19 vaccines 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Heterologous vaccination scheme vs homologous vaccination scheme

Confirmed symptomatic COVID‐19b

The review found no eligible studies for this question.

1 finding from 1 review

Efficacy and safety of COVID‐19 vaccines 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Heterologous vaccination scheme vs homologous vaccination scheme

Severe or critical COVID‐19

The review found no eligible studies for this question.

1 finding from 1 review

Efficacy and safety of COVID‐19 vaccines 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Heterologous vaccination scheme vs homologous vaccination scheme

All‐cause mortalityÂ

The review found no eligible studies for this question.

1 finding from 1 review

Efficacy and safety of COVID‐19 vaccines 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Heterologous vaccination scheme vs homologous vaccination scheme

Systemic reactogenicity events

Heterologous vaccination scheme showed no clear difference in systemic reactogenicity eventsb compared with homologous vaccination scheme (low certainty).

1 finding from 1 review

Efficacy and safety of COVID‐19 vaccines 2022 · Cochrane Headline outcomes only
RR 1.96 [0.52, 7.41]
1 study · 101 participants
Low

Heterologous vaccination scheme vs homologous vaccination scheme

Any adverse eventf

1 finding from 1 review

Efficacy and safety of COVID‐19 vaccines 2022 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 3 participants
Very low

Heterologous vaccination scheme vs homologous vaccination scheme

Serious adverse eventsk

1 finding from 1 review

Efficacy and safety of COVID‐19 vaccines 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 229 participants
Very low

Heterologous vaccination scheme vs homologous vaccination scheme

Local reactogenicity events

Heterologous vaccination scheme may leads to higher local reactogenicity eventsb compared with homologous vaccination scheme (low certainty).

1 finding from 1 review

Efficacy and safety of COVID‐19 vaccines 2022 · Cochrane Headline outcomes only
RR 11.76 [1.59, 87.14]
1 study · 101 participants
Low