Findings

What do systematic reviews say?

4 questions · 4 findings · 1 reviews · Oral Health

No studies found 0 · 0%GRADE not reported 4 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Clinical resolution (oral lesion not completely resolved) · People with a diagnosis of oral leukoplakia

1 finding from 1 review

Interventions for treating oral leukoplakia to prevent oral cancer 2016 · Cochrane All outcomes
3 to 6 months
SoF 4, Clinical resolution (not completely resolved) at 3 to 6 months: '3 studies (freeze-dried black raspberry gel, green tea extract capsules, mixed tea) did not find evidence of benefit.' No GRADE. Effects text:…
4 studies
GRADE not reported

Malignant transformation (oral cancer development) · People with a diagnosis of oral leukoplakia

1 finding from 1 review

Interventions for treating oral leukoplakia to prevent oral cancer 2016 · Cochrane All outcomes
SoF 4 (Herbal extracts vs placebo), Cancer development: SoF cell 'Not measured'. Effects text: cancer development was among the outcomes in Tsao 2009 (green tea extract) but it was not possible to analyse the data…
1 study
GRADE not reported

Improvement of histological features (not improved) · People with a diagnosis of oral leukoplakia

1 finding from 1 review

Interventions for treating oral leukoplakia to prevent oral cancer 2016 · Cochrane All outcomes
3 months
SoF 4, Histological changes (not improved) at 3 months: '2 studies (green tea extract capsules and freeze-dried raspberry gel) did not find evidence of benefit.' No GRADE. Effects text: Mallery raspberry RR 0.97…
2 studies
GRADE not reported

Safety of the intervention (adverse effects) · People with a diagnosis of oral leukoplakia

1 finding from 1 review

Interventions for treating oral leukoplakia to prevent oral cancer 2016 · Cochrane All outcomes
up to 3 months
SoF 4, Safety of the intervention up to 3 months: '3 studies measured adverse effects: green tea extract capsules caused high frequency (93%) of adverse effects of varying severity in 1 study; the mixed tea study did…
3 studies
GRADE not reported