Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

8 questions · 8 findings · 1 reviews · Epilepsy · Headline outcomes only

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 2 · 25%Moderate 6 · 75%High 0 · 0%

Closest answers

The findings closest to your search, judged one by one by TypeSafe's Jev model.

Gabapentin vs placebo

50% or greater reduction in seizure frequency Number of seizures · people with drug‐resistant focal epilepsy

Gabapentin probably leads to higher reduction in seizure frequency of ≥ 50%: primary analysisNumber of… compared with placebo (moderate certainty).

1 finding from 1 review

Gabapentin vs placebo

Treatment withdrawalNumber of participants withdrawn for any reason · people with drug‐resistant focal epilepsy

Gabapentin showed no clear difference in treatment withdrawalNumber of participants withdrawn for any reason compared with placebo (moderate certainty).

1 finding from 1 review

Gabapentin vs placebo

Adverse effects: ataxia Number of participants experiencing ataxia · people with drug‐resistant focal epilepsy

Gabapentin may leads to higher adverse effects: ataxiaNumber of participants experiencing ataxia compared with placebo (low certainty).

1 finding from 1 review