Findings

What do systematic reviews say?

7 questions · 7 findings · 1 reviews · Stroke

Sort:Best matchNewest Highest certainty Download CSV

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 14.3%Moderate 2 · 28.6%High 4 · 57.1%

Fluoxetine vs control at end of treatment,

Disability (primary analysis) · people with stroke recovery

1 finding from 1 review

Selective serotonin reuptake inhibitors (SSRIs) for stroke recovery 2021 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 5436 participants
High

Fluoxetine vs control at end of treatment,

Independent on modified Rankin score (mRS 0 to 2) (primary analysis) · people with stroke recovery

Fluoxetine showed no clear difference in independent on modified Rankin score (mRS 0 to 2) (primary analysis) compared with control at end of treatment, (high certainty).

1 finding from 1 review

Selective serotonin reuptake inhibitors (SSRIs) for stroke recovery 2021 · Cochrane Headline outcomes only
RR 0.98 [0.93, 1.03]
5 studies · 5926 participants
High

Fluoxetine vs control at end of treatment,

Neurological deficit score · people with stroke recovery

1 finding from 1 review

Selective serotonin reuptake inhibitors (SSRIs) for stroke recovery 2021 · Cochrane Headline outcomes only
no estimate extracted
30 participants
Low

Fluoxetine vs control at end of treatment,

Depressive symptoms · people with stroke recovery

1 finding from 1 review

Selective serotonin reuptake inhibitors (SSRIs) for stroke recovery 2021 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 5356 participants
High

Fluoxetine vs control at end of treatment,

Death · people with stroke recovery

Fluoxetine showed no clear difference in death compared with control at end of treatment, (moderate certainty).

1 finding from 1 review

Selective serotonin reuptake inhibitors (SSRIs) for stroke recovery 2021 · Cochrane Headline outcomes only
RR 1.01 [0.82, 1.24]
6 studies · 6090 participants
Moderate

Fluoxetine vs control at end of treatment,

Seizures · people with stroke recovery

Fluoxetine showed no clear difference in number of seizures compared with control at end of treatment, (moderate certainty).

1 finding from 1 review

Selective serotonin reuptake inhibitors (SSRIs) for stroke recovery 2021 · Cochrane Headline outcomes only
RR 1.4 [1, 1.98]
6 studies · 6080 participants
Moderate

Fluoxetine vs control at end of treatment,

Fracture · people with stroke recovery

Fluoxetine leads to higher bone fractures compared with control at end of treatment, (high certainty).

1 finding from 1 review

Selective serotonin reuptake inhibitors (SSRIs) for stroke recovery 2021 · Cochrane Headline outcomes only
RR 2.35 [1.62, 3.41]
6 studies · 6080 participants
High