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What do systematic reviews say?

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Evidence found and GRADE certainty

5 questions · 5 findings · 1 reviews · Gut

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 2 · 40%Low 0 · 0%Moderate 3 · 60%High 0 · 0%

Intervention not reported

Relapse rate at one year (all studies) · Crohn's disease patients in remission

It is very uncertain whether the intervention changes relapse rate at one year (all studies) (very low certainty).

1 finding from 1 review

Intervention not reported

Relapse rate at one year (sensitivity analysis of Belluzi 1996) · Crohn's disease patients in remission

It is very uncertain whether the intervention changes relapse rate at one year (sensitivity analysis of Belluzi 1996) (very low certainty).

1 finding from 1 review

Intervention not reported

Relapse rate at one year (only EPIC studies) · Crohn's disease patients in remission

The intervention showed no clear difference in relapse rate at one year (only EPIC studies) (moderate certainty).

1 finding from 1 review

Intervention not reported

Adverse events rate‐ Upper GI (nausea, vomiting, halitosis, heartburn, dyspepsia, dysgeusia and bloating) · Crohn's disease patients in remission

The intervention probably leads to higher adverse events rate‐ Upper GI (nausea, vomiting, halitosis,… (moderate certainty).

1 finding from 1 review