What do systematic reviews say?

Raloxifene vs placebo

It is very uncertain whether raloxifene changes mean change in BMD of the femoral neck compared with placebo (very low certainty).

• Pharmacological interventions versus placebo, no treatment or usual care for osteoporosis in people with chronic… 2021 · Cochrane Headline outcomes only
  MD 0.01 [0, 0.02]
  2 studies · 110 participants
  Very low

Any anti‐osteoporotic drugs vs placebo

• Pharmacological interventions versus placebo, no treatment or usual care for osteoporosis in people with chronic… 2021 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 6081 participants
  Very low