Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

5 questions · 5 findings · 1 reviews

No studies found 2 · 40%GRADE not reported 0 · 0%Very low 0 · 0%Low 3 · 60%Moderate 0 · 0%High 0 · 0%

Felbamate plus ASMs vs placebo plus ASMs

Number of participants free from all seizures (recorded by closed‐circuit television and electroencephalography) ‐ · Lennox‐Gastaut syndrome, any age

Felbamate plus ASMs showed no clear difference in number of participants free from all seizures (recorded by… compared with placebo plus ASMs (low certainty).

1 finding from 1 review

Felbamate plus ASMs vs placebo plus ASMs

Number of participants with adverse events leading to study discontinuation · Lennox‐Gastaut syndrome, any age

Felbamate plus ASMs showed no clear difference in number of participants with adverse events leading to study… compared with placebo plus ASMs (low certainty).

1 finding from 1 review