What do systematic reviews say?

Parenteral iron vs inactive control

• Iron therapy in anaemic adults without chronic kidney disease 2014 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 1629 participants
  Very low

Parenteral iron vs inactive control

It is very uncertain whether parenteral iron changes serious adverse events compared with inactive control (very low certainty).

• Iron therapy in anaemic adults without chronic kidney disease 2014 · Cochrane Headline outcomes only
  RR 1 [0.74, 1.34]
  7 studies · 1802 participants
  Very low

Parenteral iron vs oral iron

It is very uncertain whether parenteral iron changes mortality compared with oral iron (very low certainty).

• Iron therapy in anaemic adults without chronic kidney disease 2014 · Cochrane Headline outcomes only
  RR 1.49 [0.56, 3.94]
  6 studies · 1009 participants
  Very low

Parenteral iron vs oral iron

It is very uncertain whether parenteral iron changes proportion requiring blood transfusion compared with oral iron (very low certainty).

• Iron therapy in anaemic adults without chronic kidney disease 2014 · Cochrane Headline outcomes only
  RR 0.61 [0.24, 1.58]
  2 studies · 371 participants
  Very low

Parenteral iron vs oral iron

• Iron therapy in anaemic adults without chronic kidney disease 2014 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 44 participants
  Very low

Parenteral iron vs oral iron

• Iron therapy in anaemic adults without chronic kidney disease 2014 · Cochrane Headline outcomes only
  no estimate extracted
  6 studies · 769 participants
  Low

Parenteral iron vs oral iron

• Iron therapy in anaemic adults without chronic kidney disease 2014 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 771 participants
  Very low

Parenteral iron vs oral iron

It is very uncertain whether parenteral iron changes serious adverse events compared with oral iron (very low certainty).

• Iron therapy in anaemic adults without chronic kidney disease 2014 · Cochrane Headline outcomes only
  RR 1.23 [0.99, 1.54]
  7 studies · 1100 participants
  Very low

Parenteral iron vs inactive control

It is very uncertain whether parenteral iron changes mortality compared with inactive control (very low certainty).

• Iron therapy in anaemic adults without chronic kidney disease 2014 · Cochrane Headline outcomes only
  RR 1.04 [0.63, 1.69]
  10 studies · 2141 participants
  Very low

Parenteral iron vs inactive control

It is very uncertain whether parenteral iron changes proportion requiring blood transfusion compared with inactive control (very low certainty).

• Iron therapy in anaemic adults without chronic kidney disease 2014 · Cochrane Headline outcomes only
  RR 0.84 [0.66, 1.06]
  8 studies · 1315 participants
  Very low

Parenteral iron vs inactive control

• Iron therapy in anaemic adults without chronic kidney disease 2014 · Cochrane Headline outcomes only
  no estimate extracted
  9 studies · 1371 participants
  Very low

Intravenous vs intraosseous route

Intravenous may leads to higher insertion failures compared with intraosseous route (low certainty).

• Comparison of routes for achieving parenteral access with a focus on the management of patients with Ebola virus disease 2015 · Cochrane Headline outcomes only
  RR 3.89 [2.39, 6.33]
  2 studies · 242 participants
  Low

Intravenous vs subcutaneous route

• Comparison of routes for achieving parenteral access with a focus on the management of patients with Ebola virus disease 2015 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 4 participants
  Low

Saphenous vein cutdown vs intraosseous route

Saphenous vein cutdown showed no clear difference in insertion failures compared with intraosseous route (low certainty).

• Comparison of routes for achieving parenteral access with a focus on the management of patients with Ebola virus disease 2015 · Cochrane Headline outcomes only
  RR 4 [0.51, 31.13]
  1 study · 13 participants
  Low

Saphenous vein cutdown vs intraosseous route

• Comparison of routes for achieving parenteral access with a focus on the management of patients with Ebola virus disease 2015 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 13 participants
  Moderate

Saphenous vein cutdown vs intraosseous route

The review found no eligible studies for this question.

• Comparison of routes for achieving parenteral access with a focus on the management of patients with Ebola virus disease 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Saphenous vein cutdown vs intraosseous route

The review found no eligible studies for this question.

• Comparison of routes for achieving parenteral access with a focus on the management of patients with Ebola virus disease 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Saphenous vein cutdown vs intraosseous route

The review found no eligible studies for this question.

• Comparison of routes for achieving parenteral access with a focus on the management of patients with Ebola virus disease 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Intravenous vs intraosseous route

• Comparison of routes for achieving parenteral access with a focus on the management of patients with Ebola virus disease 2015 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 342 participants
  Moderate

Intravenous vs intraosseous route

Intravenous showed no clear difference in dislodgement of device during infusion compared with intraosseous route (low certainty).

• Comparison of routes for achieving parenteral access with a focus on the management of patients with Ebola virus disease 2015 · Cochrane Headline outcomes only
  RR 0.53 [0.18, 1.55]
  1 study · 182 participants
  Low